Social and sexual behaviors in C. elegans: the first fifty years.

Social and sexual behaviors in C. elegans: the first fifty years.
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DOI:
10.1080/01677063.2020.1838512
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发表时间:
2020-09
影响因子:
1.9
通讯作者:
Portman DS
Portman DS
中科院分区:
医学4区
文献类型:
--
作者:
Portman DS

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在1974年里程碑式的论文发表后的头25年里,大多数秀丽隐杆线虫生物学家都满足于把他们的研究对象视为孤独的生物。秀丽隐杆线虫并不缺乏令人着迷的生物学问题,但导致布伦纳选择这个物种的一些特征——尤其是它自由生活、自我受精的生活方式——似乎也降低了它有趣的社会行为的潜力。这种观点很快就改变了,在过去的二十年里,在识别和理解蠕虫之间复杂的相互作用方面取得了显著进展。越来越多的人认识到秀丽隐杆线虫的行为只能在其生态和进化的背景下进行有意义的理解,这确保了未来几年将看到同样令人兴奋的进展。
For the first 25 years after the landmark 1974 paper that launched the field, most C. elegans biologists were content to think of their subjects as solitary creatures. C. elegans presented no shortage of fascinating biological problems, but some of the features that led Brenner to settle on this species—in particular, its free-living, self-fertilizing lifestyle—also seemed to reduce its potential for interesting social behavior. That perspective soon changed, with the last two decades bringing remarkable progress in identifying and understanding the complex interactions between worms. The growing appreciation that C. elegans behavior can only be meaningfully understood in the context of its ecology and evolution ensures that the coming years will see similarly exciting progress.
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