Emergence of Different Recombinant Porcine Reproductive and Respiratory Syndrome Viruses, China.

Emergence of Different Recombinant Porcine Reproductive and Respiratory Syndrome Viruses, China.
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中国不同重组猪繁殖与呼吸综合征病毒的出现

DOI:
10.1038/s41598-018-22494-4
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发表时间:
2018-03-07
期刊:
影响因子:
4.6
通讯作者:
Yu J
Yu J
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Liu Y;Li J;Yang J;Zeng H;Guo L;Ren S;Sun W;Chen Z;Cong X;Shi J;Chen L;Du Y;Li J;Wang J;Wu J;Yu J

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2014-2015年对山东省新出现的猪繁殖与呼吸综合征病毒(PRRSV)毒株进行了流行病学调查。通过ORF 7序列比对鉴定的NADC 30株比例逐渐增加。成功分离了3株新出现的PRRSV毒株,并测定了全基因组序列。我们的研究结果表明,在中国山东省的重组菌株的重要性。两种或三种毒株(经典毒株、HP-PRRSV和/或NADC 30)存在不同程度的重组。此外,重组菌株影响新出现的菌株的致病性。
Epidemiological investigations were conducted on recently emerging porcine reproductive and respiratory syndrome virus (PRRSV) strains in Shandong province in 2014–2015. The proportion of the NADC30 strain identified by ORF7 sequence alignment has been gradually increasing. Three emerging PRRSV strains were successfully isolated, and the complete genomic sequences were determined. Our results indicate the importance of recombinant strains in Shandong province, China. There was a varied degree of recombination of two or three strains (classical, HP-PRRSV and/or NADC30). Moreover, the recombination strains affected the pathogenicity of newly emerged strains.
DOI: 10.1006/viro.1999.0056
发表时间: 1999-12-20
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