Brain activation related to combinations of gaze position, visual input, and goal-directed hand movements.

Brain activation related to combinations of gaze position, visual input, and goal-directed hand movements.
复制标题

大脑激活与注视位置、视觉输入和目标导向的手部动作的组合有关。

DOI:
10.1093/cercor/bhq205
复制
发表时间:
2011
期刊:
Cerebral cortex (New York, N.Y. : 1991)
影响因子:
--
通讯作者:
Sanes,JeromeN
Sanes,JeromeN
中科院分区:
--
文献类型:
--
作者:
Bédard,Patrick;Wu,Min;Sanes,JeromeN

文献摘要

参考文献

相似文献

人类通过将视觉目标转化为行动命令来接触和获取物体。大脑如何将视觉框架中指定的目标与信号整合到一个合适的行动计划框架中,需要澄清视觉输入本身是否与凝视位置相互作用以制定行动计划。为了进一步评估视觉-运动整合的大脑控制,我们使用功能性磁共振成像评估了大脑激活。当人们从中间向左或向右凝视时,人们会朝着可见的或记忆中的目标进行目标导向的运动。我们使用延迟响应任务将运动计划与性能分离开来,并通过其在延迟期间的可用性来操纵目标可见性,或者在开始后500毫秒将其关闭。我们发现凝视方向对计划过程中的大脑激活有很强的影响,目标可见性和凝视方向对表演过程中顶叶和运动前皮质(PM)、小脑和基底神经节的运动相关激活有交互作用,对可见目标的右凝视激活更多,而对指向记忆目标的运动没有凝视调节。这些结果证明了凝视位置对PM和运动相关过程的影响,并提供了视觉信号如何与凝视位置相互作用以将视觉输入转化为运动目标的新信息。
Humans reach to and acquire objects by transforming visual targets into action commands. How the brain integrates goals specified in a visual framework to signals into a suitable framework for an action plan requires clarification whether visual input, per se, interacts with gaze position to formulate action plans. To further evaluate brain control of visual–motor integration, we assessed brain activation, using functional magnetic resonance imaging. Humans performed goal-directed movements toward visible or remembered targets while fixating gaze left or right from center. We dissociated movement planning from performance using a delayed-response task and manipulated target visibility by its availability throughout the delay or blanking it 500 ms after onset. We found strong effects of gaze orientation on brain activation during planning and interactive effects of target visibility and gaze orientation on movement-related activation during performance in parietal and premotor cortices (PM), cerebellum, and basal ganglia, with more activation for rightward gaze at a visible target and no gaze modulation for movements directed toward remembered targets. These results demonstrate effects of gaze position on PM and movement-related processes and provide new information how visual signals interact with gaze position in transforming visual inputs into motor goals.
DOI: 10.1152/jn.91194.2008
发表时间: 2009-06-01
影响因子: 2.5
作者:
Beurze, S. M.;de Lange, F. P.;Medendorp, W. P.
通讯作者: Medendorp, W. P.
灵长类运动前皮层与眼手协调相关的神经元活动
DOI: --
发表时间: 1999
影响因子: 2
作者:
C. Jouffrais;D. Boussaoud
通讯作者: D. Boussaoud
DOI: 10.1152/jn.2001.85.1.462
发表时间: 2001-01-01
影响因子: 2.5
作者:
Ferraina, S;Battaglia-Mayer, A;Caminiti, R
通讯作者: Caminiti, R
DOI: 10.1523/jneurosci.23-15-06209.2003
发表时间: 2003-07
期刊: The Journal of Neuroscience
影响因子: --
作者:
W. Medendorp;Herbert C. Goltz;T. Vilis;J. Crawford
通讯作者: W. Medendorp;Herbert C. Goltz;T. Vilis;J. Crawford
坐标变换首先在初级运动皮层的下游完成
DOI: --
发表时间: 2008
影响因子: 5.3
作者:
Yuval Yanai;Nofya Adamit;Z. Israel;R. Harel;Y. Prut
通讯作者: Y. Prut