Few Structural Brain Changes Associated With Moderate-Intensity Interval Training and Low-Intensity Continuous Training in a Randomized Trial of Fitness and Older Adults.
Few Structural Brain Changes Associated With Moderate-Intensity Interval Training and Low-Intensity Continuous Training in a Randomized Trial of Fitness and Older Adults.
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DOI：
10.1123/japa.2019-0352
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发表时间：
2021-06-01
影响因子：
1.5
通讯作者：
Bryan, Angela D.
中科院分区：
文献类型：
--
作者：
Martin-Willett, Renee;Ellingson, Jarrod E.;Fries, Jill;Helmuth, Timothy;Karoly, Hollis;Giordano, Gregory;Calhoun, Vince D.;Bryan, Angela D.
本研究采用随机对照试验，以检查楔前叶，海马，尾状核，海马和壳核的结构变化是否与运动有关。共有197名没有痴呆症证据的健康老年人参加了为期16周的中等强度间歇训练或低强度连续训练。右侧海马的大小减少，因此时间的影响是显着的，但与条件的相互作用不是。对于左侧海马，在低强度持续训练条件下，大小减小，但在中等强度持续训练加间歇训练条件下，大小在趋势水平上增加。最后，有一个显着的时间与条件的相互作用，如左前额叶的厚度增加低强度的连续训练和减少中等强度的连续训练加间歇训练。很少有结构变化与运动干预有关。未来的研究应该在更长的时间内检查运动对高危或临床人群大脑结构的影响。
This study utilized a randomized control trial to examine whether structural changes in the precuneus, insula, caudate, hippocampus, and putamen were related to exercise. A total of 197 healthy older adults with no evidence of dementia participated in moderate-intensity interval training or low-intensity continuous training for 16 weeks. Size decreased in the right hippocampus such that the effect of time was significant but the interaction with condition was not. For the left hippocampus, size decreased in the low-intensity continuous training condition but increased in the moderate-intensity continuous training plus interval training condition at the trend level. Finally, there was a significant time-by-condition interaction such that the thickness of the left insula increased for low-intensity continuous training and decreased for moderate-intensity continuous training plus interval training. Few structural changes were associated with the exercise intervention. Future studies should examine the effects of exercise on brain structure in high-risk or clinical populations for a longer period of time.
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影响因子：
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作者：
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DOI：
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发表时间：
2011-02-15
影响因子：
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作者：
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影响因子：
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