Comparison of polyfluoroalkyl compound concentrations in maternal serum and amniotic fluid: a pilot study.
Comparison of polyfluoroalkyl compound concentrations in maternal serum and amniotic fluid: a pilot study.
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DOI：
10.1016/j.reprotox.2012.05.039
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发表时间：
2012-11
期刊：
影响因子：
--
通讯作者：
Engel SM
中科院分区：
文献类型：
--
作者：
Stein CR;Wolff MS;Calafat AM;Kato K;Engel SM
The extent to which polyfluoroalkyl compounds (PFCs) are detectable in amniotic fluid is unknown. Using paired samples from 28 women, we compared the concentration of 8 PFCs measured in serum, the standard matrix for assessing human exposure, amniotic fluid from routine amniocentesis, and urine. Perfluorooctanoate (PFOA), perfluorononanoate (PFNA), perfluorooctane sulfonate (PFOS), and perfluorohexane sulfonate (PFHxS) were detected in all maternal serum samples. The number of amniotic fluid samples with detectable concentrations differed by PFC (PFOA n=24; PFNA n=10; PFOS n=9; PFHxS n=4). The correlation coefficient between maternal serum and amniotic PFC levels varied considerably by PFC (PFOA ρ=0.64, p<0.001; PFNA ρ=0.05, p=0.9; PFOS ρ=0.76, p=0.01; PFHxS ρ=0.80, p=0.2). Using linear regression, PFOA appeared to be commonly detected in amniotic fluid if the serum concentration exceeded approximately 1.5 ng/mL whereas PFOS was rarely detected in amniotic fluid until the serum concentration was about 5.5 ng/mL. No PFCs were detected in urine.
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影响因子：
10.4
作者：
Calafat, Antonia M;Wong, Lee-Yang;Kuklenyik, Zsuzsanna;Reidy, John A;Needham, Larry L
通讯作者：
Needham, Larry L
DOI：
10.1016/j.reprotox.2009.02.012
发表时间：
2009-06
期刊：
Reproductive toxicology (Elmsford, N.Y.)
影响因子：
--
作者：
Fenton SE;Reiner JL;Nakayama SF;Delinsky AD;Stanko JP;Hines EP;White SS;Lindstrom AB;Strynar MJ;Petropoulou SE
通讯作者：
Petropoulou SE
影响因子：
8.9
作者：
Kim, Seung-Kyu;Lee, Kyu Tae;Lee, Jong-Hyeon
通讯作者：
Lee, Jong-Hyeon
影响因子：
5
作者：
Fei, Chunyuan;McLaughlin, Joseph K.;Olsen, Jorn
通讯作者：
Olsen, Jorn
影响因子：
11.4
作者：
Fromme, Hermann;Mosch, Christine;Volkel, Wolfgang
通讯作者：
Volkel, Wolfgang