Clothianidin-resistant Anopheles gambiae adult mosquitoes from Yaoundé, Cameroon, display reduced susceptibility to SumiShield® 50WG, a neonicotinoid formulation for indoor residual spraying.
Clothianidin-resistant Anopheles gambiae adult mosquitoes from Yaoundé, Cameroon, display reduced susceptibility to SumiShield® 50WG, a neonicotinoid formulation for indoor residual spraying.
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DOI：
10.1186/s12879-024-09030-8
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发表时间：
2024-01-25
影响因子：
3.7
通讯作者：
Kamdem, Colince
中科院分区：
文献类型：
--
作者：
Fouet, Caroline;Ashu, Fred A.;Ambadiang, Marilene M.;Tchapga, Williams;Wondji, Charles S.;Kamdem, Colince
蚊子幼虫长期接触农药残留和交叉耐药机制是对用于病媒控制的杀虫剂产生耐受性的主要驱动因素。这引起了人们对噻虫胺功效的担忧，噻虫胺是一种经过室内滞留喷洒 (IRS) 预审的农业新烟碱类杀虫剂。使用标准生物测定，我们测试了降低对噻虫胺的敏感性是否会影响 SumiShield® 50WG 的功效，SumiShield® 50WG 是四种含有噻虫胺的新 IRS 配方之一。我们同时监测了对噻虫胺和 SumiShield 50WG 的敏感性，测试了冈比亚按蚊成虫。 coluzzii 和 Culex sp 采样自喀麦隆雅温得的城市、郊区和农业地区。我们发现，在这个地理区域，对活性成分的敏感性水平可以预测 SumiShield 50WG 的功效。该制剂对于暴露于特定浓度的噻虫胺 72 小时内达到 100% 死亡率的人群非常有效。相比之下，接触 SumiShield 50WG 的 7 天内死亡率稳定在 75.4±3.5%。从一个农场收集的冈比亚成虫，该农场为保护作物而喷洒两种新烟碱类啶虫脒和吡虫啉，可能会导致对噻虫胺产生抗药性。尽管该研究的地理范围相对较小，但研究结果表明，交叉耐药性可能会影响一些新 IRS 制剂的功效，并且在新烟碱类耐药性出现的地区可以优先考虑替代化合物。
Chronic exposure of mosquito larvae to pesticide residues and cross-resistance mechanisms are major drivers of tolerance to insecticides used for vector control. This presents a concern for the efficacy of clothianidin, an agricultural neonicotinoid prequalified for Indoor Residual Spraying (IRS). Using standard bioassays, we tested if reduced susceptibility to clothianidin can affect the efficacy of SumiShield® 50WG, one of four new IRS formulations containing clothianidin. We simultaneously monitored susceptibility to clothianidin and to SumiShield 50WG, testing adults of Anopheles gambiae, An. coluzzii and Culex sp sampled from urban, suburban and agricultural areas of Yaoundé, Cameroon. We found that in this geographic area, the level of susceptibility to the active ingredient predicted the efficacy of SumiShield 50WG. This formulation was very potent against populations that reached 100% mortality within 72 h of exposure to a discriminating concentration of clothianidin. By contrast, mortality leveled off at 75.4 ± 3.5% within 7 days of exposure to SumiShield 50WG in An. gambiae adults collected from a farm where the spraying of the two neonicotinoids acetamiprid and imidacloprid for crop protection is likely driving resistance to clothianidin. Despite the relatively small geographic extend of the study, the findings suggest that cross-resistance may impact the efficacy of some new IRS formulations and that alternative compounds could be prioritized in areas where neonicotinoid resistance is emerging.
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影响因子：
3
作者：
Antonio-Nkondjio C;Tene Fossog B;Kopya E;Poumachu Y;Menze Djantio B;Ndo C;Tchuinkam T;Awono-Ambene P;Wondji CS
通讯作者：
Wondji CS
影响因子：
2.9
作者：
Assatse T;Tchouakui M;Mugenzi L;Menze B;Nguiffo-Nguete D;Tchapga W;Kekeunou S;Wondji CS
通讯作者：
Wondji CS
影响因子：
1.1
作者：
Abdallah, Ibrahim Saleh;Abou-Yousef, Hala Mohamed;Kandil, Mohammed Abd El-Hady
通讯作者：
Kandil, Mohammed Abd El-Hady
DOI：
10.1016/s0140-6736(15)00417-1
发表时间：
2016-04-23
期刊：
Lancet (London, England)
影响因子：
--
作者：
Hemingway J;Ranson H;Magill A;Kolaczinski J;Fornadel C;Gimnig J;Coetzee M;Simard F;Roch DK;Hinzoumbe CK;Pickett J;Schellenberg D;Gething P;Hoppé M;Hamon N
通讯作者：
Hamon N
影响因子：
3.2
作者：
Agossa FR;Padonou GG;Koukpo CZ;Zola-Sahossi J;Azondekon R;Akuoko OK;Ahoga J;N'dombidje B;Akinro B;Fassinou AJYH;Sezonlin M;Akogbeto MC
通讯作者：
Akogbeto MC