Sleep, sleep disturbance, and fertility in women.

Sleep, sleep disturbance, and fertility in women.
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DOI:
10.1016/j.smrv.2014.10.005
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发表时间:
2015-08
影响因子:
10.5
通讯作者:
Gracia, Clarisa R.
Gracia, Clarisa R.
中科院分区:
医学1区
文献类型:
--
作者:
Kloss, Jacqueline D.;Perlis, Michael L.;Zamzow, Jessica A.;Culnan, Elizabeth J.;Gracia, Clarisa R.

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睡眠和睡眠障碍越来越被认为是妇女健康和福祉的决定因素,特别是在月经周期、怀孕和更年期的背景下。然而,目前对睡眠数量和质量是否影响生育能力知之甚少。也就是说,睡眠和/或睡眠障碍在多大程度上以及通过何种机制影响生育能力?本综述的目的是综合什么是已知的睡眠障碍与生殖能力。提供了一个模型,据此描述了压力、睡眠失调和昼夜节律失调与不孕症的潜在相关性。最终,如果睡眠障碍与不孕症有关,那么临床干预的新途径可能是可能的。
Sleep and sleep disturbances are increasingly recognized as determinants of women’s health and well-being, particularly in the context of the menstrual cycle, pregnancy, and menopause. At present, however, little is known about whether fertility is affected by sleep quantity and quality. That is, to what degree, and by what mechanisms, do sleep and/or its disturbances affect fertility? The purpose of this review is to synthesize what is known about sleep disturbances in relation to reproductive capacity. A model is provided, whereby stress, sleep dysregulation, and circadian misalignment are delineated for their potential relevance to infertility. Ultimately, if it is the case that sleep disturbance is associated with infertility, new avenues for clinical intervention may be possible.
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