Genetics-based methods for agricultural insect pest management.
Genetics-based methods for agricultural insect pest management.
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DOI：
10.1111/afe.12241
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发表时间：
2018-05
影响因子：
1.6
通讯作者：
Bonsall MB
中科院分区：
文献类型：
--
作者：
Alphey N;Bonsall MB
昆虫不育技术是一种区域范围内的害虫控制方法，通过释放大量饲养的不育昆虫，减少农业害虫的数量，然后与野生昆虫竞争配偶。当代基于遗传学的技术使用纯合子的昆虫来获得可抑制的显性致死遗传结构，而不是通过照射进行绝育。农业害虫物种的基因工程菌株，包括小菜蛾和地中海角蝇等果蝇，已经被开发出只对雌性具有致命性的菌株。表达杀虫毒素的转基因作物被广泛应用；如果毒素抗性在害虫种群中传播，这些作物的经济效益就会丧失。主要的抗性管理方法是高剂量/避难策略，要求无毒素作物作为杀虫作物附近的避难所，以及足够高的毒素剂量以杀死野生型昆虫和抗性等位基因杂合的昆虫。大量释放毒素敏感的工程雄蚊（携带雌性致死基因），以及抑制种群数量，可以大大延缓或逆转耐药性的传播。这些转基因昆虫技术可以形成有效的抗性管理策略。我们概述了将遗传昆虫控制系统应用于田间实施的一些政策考虑。
The sterile insect technique is an area‐wide pest control method that reduces agricultural pest populations by releasing mass‐reared sterile insects, which then compete for mates with wild insects. Contemporary genetics‐based technologies use insects that are homozygous for a repressible dominant lethal genetic construct rather than being sterilized by irradiation. Engineered strains of agricultural pest species, including moths such as the diamondback moth Plutella xylostella and fruit flies such as the Mediterranean fruit fly Ceratitis capitata, have been developed with lethality that only operates on females. Transgenic crops expressing insecticidal toxins are widely used; the economic benefits of these crops would be lost if toxin resistance spread through the pest population. The primary resistance management method is a high‐dose/refuge strategy, requiring toxin‐free crops as refuges near the insecticidal crops, as well as toxin doses sufficiently high to kill wild‐type insects and insects heterozygous for a resistance allele. Mass‐release of toxin‐sensitive engineered males (carrying female‐lethal genes), as well as suppressing populations, could substantially delay or reverse the spread of resistance. These transgenic insect technologies could form an effective resistance management strategy. We outline some policy considerations for taking genetic insect control systems through to field implementation.
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DOI：
10.1098/rsif.2013.1071
发表时间：
2014-04-06
期刊：
Journal of the Royal Society, Interface
影响因子：
--
作者：
Alphey N;Bonsall MB
通讯作者：
Bonsall MB
影响因子：
3.8
作者：
Carvalho DO;McKemey AR;Garziera L;Lacroix R;Donnelly CA;Alphey L;Malavasi A;Capurro ML
通讯作者：
Capurro ML
影响因子：
3.7
作者：
Alphey N;Alphey L;Bonsall MB
通讯作者：
Bonsall MB
影响因子：
5.4
作者：
Ant T;Koukidou M;Rempoulakis P;Gong HF;Economopoulos A;Vontas J;Alphey L
通讯作者：
Alphey L
DOI：
10.1007/978-0-387-78225-6_9
发表时间：
2008-01-01
期刊：
TRANSGENESIS AND THE MANAGEMENT OF VECTOR-BORNE DISEASE
影响因子：
--
作者：
Bourtzis, Kostas
通讯作者：
Bourtzis, Kostas