Diffusion tensor imaging for understanding brain development in early life.

Diffusion tensor imaging for understanding brain development in early life.
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DOI:
10.1146/annurev-psych-010814-015340
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发表时间:
2015-01-03
影响因子:
24.8
通讯作者:
Miller MI
Miller MI
中科院分区:
心理学1区
文献类型:
--
作者:
Qiu A;Mori S;Miller MI

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人类的大脑在怀孕的最后几周和出生后的头两年迅速发育。弥散张量成像(DTI)是一种独特的体内成像技术,可以对大脑白质解剖结构进行三维可视化。它被认为是研究早期大脑发育的一个有价值的工具。在本文中,我们首先介绍了DTI技术。然后,我们回顾了DTI在胎儿期和婴儿期白质发育的发现,以及DTI在理解早产儿神经认知发育和大脑异常方面的应用。最后,我们讨论了DTI的局限性以及研究白质髓鞘形成的潜在有价值的成像技术。
The human brain rapidly develops during the final weeks of gestation and in the first two years following birth. Diffusion tensor imaging (DTI) is a unique in vivo imaging technique that allows three-dimensional visualization of the white matter anatomy in the brain. It has been considered to be a valuable tool for studying brain development in early life. In this review, we first introduce the DTI technique. We then review DTI findings on white matter development at the fetal stage and in infancy as well as DTI applications for understanding neurocognitive development and brain abnormalities in preterm infants. Finally, we discuss limitations of DTI and potential valuable imaging techniques for studying white matter myelination.
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