The hippocampus and inferential reasoning: building memories to navigate future decisions.
The hippocampus and inferential reasoning: building memories to navigate future decisions.
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DOI：
10.3389/fnhum.2012.00070
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发表时间：
2012
影响因子：
2.9
通讯作者：
Preston AR
中科院分区：
文献类型：
--
作者：
Zeithamova D;Schlichting ML;Preston AR
推理的一个重要方面是能够在没有一起经历的项目或事件之间形成关系。这篇评论考虑了关于海马体在记忆编码和提取过程中成功推理的作用的不同观点。直觉上，推理可以被认为是一个逻辑过程，通过这个过程，个体现有记忆的元素被检索和重组，以回答新的问题。这种灵活的检索是由海马子服务，并被认为需要专门的海马编码机制，离散编码事件，使事件元素是单独访问的记忆。除了基于检索的推理，最近的研究还集中在海马过程中，支持在编码过程中通过多种经验获得的信息的组合。这种机制表明，通过在新的经历中回忆过去的事件，可以在新形成的记忆和现有的记忆之间建立联系。因此，这种大脑介导的记忆整合是相关记忆网络形成的基础，这种网络超越了直接经验，可以预测未来对项目和事件之间关系的判断。我们还讨论了整合编码的背景下，新出现的证据，海马体的形成模式，以及海马体功能的前瞻性理论，表明记忆是积极构建，以预测未来的决定和行动。
A critical aspect of inferential reasoning is the ability to form relationships between items or events that were not experienced together. This review considers different perspectives on the role of the hippocampus in successful inferential reasoning during both memory encoding and retrieval. Intuitively, inference can be thought of as a logical process by which elements of individual existing memories are retrieved and recombined to answer novel questions. Such flexible retrieval is sub-served by the hippocampus and is thought to require specialized hippocampal encoding mechanisms that discretely code events such that event elements are individually accessible from memory. In addition to retrieval-based inference, recent research has also focused on hippocampal processes that support the combination of information acquired across multiple experiences during encoding. This mechanism suggests that by recalling past events during new experiences, connections can be created between newly formed and existing memories. Such hippocampally mediated memory integration would thus underlie the formation of networks of related memories that extend beyond direct experience to anticipate future judgments about the relationships between items and events. We also discuss integrative encoding in the context of emerging evidence linking the hippocampus to the formation of schemas as well as prospective theories of hippocampal function that suggest memories are actively constructed to anticipate future decisions and actions.
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影响因子：
2.9
作者：
Addis DR;Schacter DL
通讯作者：
Schacter DL
DOI：
10.1073/pnas.94.13.7109
发表时间：
1997-06-24
影响因子：
11.1
作者：
Dusek, JA;Eichenbaum, H
通讯作者：
Eichenbaum, H
影响因子：
3.5
作者：
DeVito, Loren M.;Kanter, Benjamin R.;Eichenbaum, Howard
通讯作者：
Eichenbaum, Howard
影响因子：
2.4
作者：
Frank, MJ;Rudy, JW;O'Reilly, RC
通讯作者：
O'Reilly, RC
影响因子：
64.8
作者：
Bunsey, M;Eichenbaum, H
通讯作者：
Eichenbaum, H