Patterns of expression of class I antigens in the tissues of congenic strains of rat.
Patterns of expression of class I antigens in the tissues of congenic strains of rat.
复制标题
I类抗原在大鼠同源品系组织中的表达模式。
DOI:
10.1089/hyb.1985.4.27
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发表时间:
1985
期刊:
影响因子:
--
通讯作者:
Iannaccone,PM
中科院分区:
文献类型:
--
作者:
Weinberg,WC;Deamant,FD;Iannaccone,PM
A comparative study of expression of class I major histocompatibility (MHC) antigens among lung, spleen, kidney, heart, liver, and brain tissues of the rat was performed. Monoclonal antibodies (MAbs) against RT1Aadeterminants were conjugated to125I and applied to frozen sections. Resulting autoradiograms showed antigen reactivity in lymphoid tissue, bronchial and alveolar epithelium, and endothelium of the lung. The Iymphoid tissue of the lung and spleen demonstrated the antigen after shorter autoradiographic exposures than was required for the epithelial components of these organs. The kidneys were heavily labeled over the glomeruli, but less intensely over the tubular epithelium. RT1A antigen content of capillary endothelium of the heart was demonstrable before that of the muscle bundles. In the liver, autoradiographic sections revealed high determinant density in sinusoidal regions. Brain sections show reproducibly low levels of labeling, with the exception of vascular structures. All of these tissues from PVG-RT1cand PVG-RT1uanimals show only background labeling.
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影响因子:
3.2
作者:
B. Ponder;M. M. Wilkinson;M. Wood;J. Westwood
通讯作者:
J. Westwood
影响因子:
6.2
作者:
S. J. Hausman;J. Palm
通讯作者:
J. Palm
影响因子:
64.8
作者:
A. G. Gervais
通讯作者:
A. G. Gervais
DOI:
--
发表时间:
1982
期刊:
Pathology (Sydney)
影响因子:
--
作者:
W. Hancock;N. Kraft;R. Atkins
通讯作者:
R. Atkins
影响因子:
64.8
作者:
GALFRE, G;HOWE, SC;HOWARD, JC
通讯作者:
HOWARD, JC