Copper sulfide nanoparticles as a new class of photoacoustic contrast agent for deep tissue imaging at 1064 nm.
Copper sulfide nanoparticles as a new class of photoacoustic contrast agent for deep tissue imaging at 1064 nm.
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DOI:
10.1021/nn302782y
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发表时间:
2012-08-28
期刊:
影响因子:
17.1
通讯作者:
Li, Chun
中科院分区:
文献类型:
--
作者:
Ku, Geng;Zhou, Min;Song, Shaoli;Huang, Qian;Hazle, John;Li, Chun
Photoacoustic tomography (PAT) is an emerging molecular imaging modality. Here, we demonstrate use of semiconductor copper sulfide nanoparticles (CuS NP) for PAT with an Nd:YAG laser at a wavelength of 1064 nm. CuS NP allowed visualization of mouse brain after intracranial injection, rat lymph nodes 12 mm below the skin after interstitial injection, and CuS NP-containing agarose gel embedded in chicken breast muscle at the depth of ~ 5 cm. This imaging approach has great potential for molecular imaging of breast cancer.
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