Assessment of Acupoint Therapy of Traditional Chinese Medicine on Cough Variant Asthma: A Meta-analysis.
Assessment of Acupoint Therapy of Traditional Chinese Medicine on Cough Variant Asthma: A Meta-analysis.
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DOI：
10.1155/2022/4168308
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发表时间：
2022
影响因子：
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通讯作者：
Zhang, Qingling
中科院分区：
文献类型：
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作者：
Tu, Hengjia;Zhang, Qingling
穴位贴敷在中国已被用于治疗各种疾病的年龄。咳嗽变异性哮喘（CVA）的主要临床表现是夜间发作性咳嗽。中药穴位贴敷疗法是治疗咳嗽变异性哮喘的有效方法。本研究旨在系统评价中医穴位贴敷疗法治疗咳嗽变异性哮喘的疗效。从数据库建立至2021年7月4日，在多个数据库（n = 8）中进行与穴位贴敷与非穴位贴敷治疗咳嗽变异性哮喘比较相关的计算机综合检索。检索了关于人体原始研究的英文和中文文献。两位独立的作者提取了数据，通过讨论解决了分歧。采用科克伦提供的ReviewManager 5.3软件对随机对照试验进行Meta分析。采用科克伦手册工具分析实验质量和风险偏倚。本研究共纳入了13篇随机对照临床文章（沿着）和1237例患者。Meta分析结果显示，穴位贴敷治疗的总有效率优于非穴位贴敷治疗（RD = 0.13，95% CI（0.09，0.17），Z = 6.70，P < 0.00001）。穴位贴敷可改善患者肺功能，肺功能指标FVC（平均差异= 0.55，95%置信区间（0.42，0.68），Z = 8.40，P < 0.00001），FEV 1（MD = 0.35，95% CI（0.23，0.47），Z = 5.86，P < 0.00001），FEV1/FVC（%）（MD = 12.68，95% CI（4.32，21.03），Z = 2.97，P = 0.003），FEV1（%）穴位贴敷治疗组患者的平均呼气流速（MD）和呼气峰流速（PEF）均较治疗前明显增加（MD = 8.63，95% CI（8.01，9.25），Z = 27.44，P < 0.00001），呼气峰流速（day）较治疗前明显增加（MD = 0.62，95% CI（0.52，0.71），Z = 12.40，P < 0.00001）。此外，穴位贴敷可能降低免疫球蛋白E（MD =-54.58，95%CI（-63.54，-45.61），Z = 11.93，P < 0.00001）和EOS（MD =-0.21，95%CI（-0.35，-0.06），Z = 2.77，P = 0.006）水平。CVA患者的LCQ（莱斯特咳嗽问卷）总分也增加（MD = 2.30，95% CI（1.55，3.06），Z = 5.98，P < 0.00001）。穴位贴敷疗法对控制咳嗽变异性哮喘的症状有效。对改善患者的肺功能和生活质量也有积极作用。它还可以降低患者的嗜酸性粒细胞水平和外周血IgE水平。
Acupoint application has been used in China to treat various illnesses for ages. In cough variant asthma (CVA), the main clinical sign is episodic night cough. Acupoint application therapy of traditional Chinese medicine is an effective procedure to treat cough variant asthma. The current study is designed to systematically assess the effectiveness of acupoint application therapy in traditional medicine for patients with cough variant asthma. The comprehensive computer retrieval related to comparison between acupoint application and nonacupoint application therapy for cough variant asthma was carried out in various databases (n = 8) from database establishment until July 4, 2021. Both English and Chinese articles about original investigations in humans were searched. Two independent authors extracted the data, and disagreements were resolved by discussion. ReviewManager 5.3 software provided by Cochrane did a meta-analysis of selected randomized controlled trials (RCTs). Quality of experimentation and risk bias were analyzed by the Cochrane Handbook tool. A total of thirteen randomized controlled clinical articles along with 1237 patients were included in the study. Findings of meta-analysis showed that compared with nonacupoint application treatment, the total effective rate of acupoint application treatment is more effective (RD = 0.13, 95% CI (0.09, 0.17), Z = 6.70, P < 0.00001). Besides, acupoint application can improve patients' lung function, the lung function index FVC (mean difference = 0.55, 95% confidence interval (0.42, 0.68), Z = 8.40, P < 0.00001), FEV1 (MD = 0.35, 95% CI (0.23, 0.47), Z = 5.86, P < 0.00001), FEV1/FVC (%) (MD = 12.68, 95% CI (4.32, 21.03), Z = 2.97, P = 0.003), FEV1 (%) (MD = 8.63, 95% CI (8.01, 9.25), Z = 27.44, P < 0.00001), and PEF (day) (MD = 0.62, 95% CI (0.52, 0.71), Z = 12.40, P < 0.00001) of patients treated by acupoint application therapy were increased. Moreover, acupoint application might lower the level of immunoglobulin E (MD = −54.58, 95% CI (−63.54, −45.61), Z = 11.93, P < 0.00001) and EOS (MD = −0.21, 95% CI (−0.35, −0.06), Z = 2.77, P = 0.006). The LCQ (Leicester cough questionnaire) total score of CVA patients was also increased (MD = 2.30, 95% CI (1.55, 3.06), Z = 5.98, P < 0.00001). Acupoint application therapy is effective in controlling symptoms of CVA. It also has a positive effect in improving lung function and life quality of patients. It can reduce the eosinophil levels and peripheral blood IgE levels of patients as well.
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DOI：
10.1186/1745-9974-9-18
发表时间：
2013-07-08
期刊：
Cough (London, England)
影响因子：
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作者：
Lai K;Pan J;Chen R;Liu B;Luo W;Zhong N
通讯作者：
Zhong N
影响因子：
2.1
作者：
Lama, M.;Chatterjee, M.;Chaudhuri, T. K.
通讯作者：
Chaudhuri, T. K.
影响因子：
2.1
作者：
Huang, Shu-Jung;Lin, Li-Lun;Huang, Jing-Long
通讯作者：
Huang, Jing-Long
针灸对哮喘大鼠具有不依赖糖皮质激素的积极作用
DOI：
10.1136/acupmed-2015-010934
发表时间：
2016-12
期刊：
Acupuncture in medicine : journal of the British Medical Acupuncture Society
影响因子：
--
作者：
Wang WQ;Xu YD;Cui LP;Yin LM;Wang Y;Liu YY;Yang YQ
通讯作者：
Yang YQ
DOI：
10.1155/2022/5589433
发表时间：
2022
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
通讯作者：
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