Rostral Intralaminar Thalamus Engagement in Cognition and Behavior.

Rostral Intralaminar Thalamus Engagement in Cognition and Behavior.
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DOI:
10.3389/fnbeh.2021.652764
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发表时间:
2021
影响因子:
3
通讯作者:
Mathur BN
Mathur BN
中科院分区:
医学3区
文献类型:
--
作者:
Cover KK;Mathur BN

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丘脑吻侧板内核(rILN)是包括中央内侧核、中央旁核和中央外侧核的神经元的连续带。在传入和传出连接以及生理和突触特性方面,rILN与丘脑中继核(如外侧膝状体核)和尾侧板内核(如束旁核)都不同。RILN活性与一系列神经功能和行为相关,包括唤醒、疼痛、执行功能和动作控制。在这里,我们回顾这一证据支持的作用,rILN在整合唤醒,执行和运动反馈信息。鉴于RILN的预测纹状体,杏仁核,感觉以及执行皮层,我们建议,这样的功能使RILN调制认知和运动资源,以满足任务依赖的行为参与的需求。
The thalamic rostral intralaminar nuclei (rILN) are a contiguous band of neurons that include the central medial, paracentral, and central lateral nuclei. The rILN differ from both thalamic relay nuclei, such as the lateral geniculate nucleus, and caudal intralaminar nuclei, such as the parafascicular nucleus, in afferent and efferent connectivity as well as physiological and synaptic properties. rILN activity is associated with a range of neural functions and behaviors, including arousal, pain, executive function, and action control. Here, we review this evidence supporting a role for the rILN in integrating arousal, executive and motor feedback information. In light of rILN projections out to the striatum, amygdala, and sensory as well as executive cortices, we propose that such a function enables the rILN to modulate cognitive and motor resources to meet task-dependent behavioral engagement demands.
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