Smoking and risk of erectile dysfunction: systematic review of observational studies with meta-analysis.
Smoking and risk of erectile dysfunction: systematic review of observational studies with meta-analysis.
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DOI：
10.1371/journal.pone.0060443
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Lu Z
中科院分区：
文献类型：
--
作者：
Cao S;Yin X;Wang Y;Zhou H;Song F;Lu Z
最近有许多关于吸烟与勃起功能障碍（艾德）风险的观察性研究，吸烟是否会增加艾德的风险仍然没有定论。本荟萃分析的目的是综合评估吸烟与ED风险之间关系的研究证据。我们于2013年1月检索了PubMed、Embase、Web of Science和Scopus，以确定评估吸烟与ED之间关系的队列和病例对照研究。纳入研究的研究质量由Newcastle-Ottawa量表评估。随机效应荟萃分析用于联合收割机合并纳入研究的结果。纳入了四项前瞻性队列研究和四项病例对照研究，涉及28586名参与者。由于纳入病例对照研究后存在显著异质性，前瞻性队列研究的一致性结果被认为更准确，与非吸烟者相比，在前瞻性队列研究中，当前吸烟者的艾德总体比值比为1.51（95%CI：1.34 ~ 1.71），既往吸烟者的总体比值比为1.29（95%CI：1.07 ~ 1.47）。未发现发表偏倚的证据，流行病学研究证据提示吸烟，尤其是当前吸烟，可能显著增加艾德的风险
There are many recent observational studies on smoking and risk of erectile dysfunction (ED) and whether smoking increases the risk of ED is still inconclusive. The objective of this meta-analysis was to synthesize evidence from studies that evaluated the association between smoking and the risk of ED. We searched PubMed, Embase, Web of Science, and Scopus in January 2013 to identify cohort and case-control studies that evaluated the association between smoking and ED. Study quality of included studies was assessed by the Newcastle-Ottawa scale. Random-effects meta-analyses were used to combine the results of included studies. Four prospective cohort studies and four case-control studies involving 28, 586 participants were included. Because of significant heterogeneity after including case-control studies in meta-analysis, the consistent results of prospective cohort studies were considered more accurate, Because of significant heterogeneity after including case-control studies in meta-analysis, the consistent results of prospective cohort studies were considered more accurate, Compared with non-smokers, the overall odd ratio of ED in prospective cohort studies was 1.51(95% CI: 1.34 to 1.71) for current smokers, and it was 1.29 (95% CI: 1.07 to 1.47) for former smokers. Evidence of publication bias was not found. Evidence from epidemiological studies suggests that smoking, especially current smoking, may significantly increase the risk of ED
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影响因子：
24
作者：
Dong, Jia-Yi;Zhang, Yong-Hong;Qin, Li-Qiang
通讯作者：
Qin, Li-Qiang
影响因子：
5.1
作者：
Tengs, TO;Osgood, ND
通讯作者：
Osgood, ND
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
影响因子：
--
作者：
Elbendary, Mohamed A.;El-Gamal, Osama M.;Salem, Khaled A.
通讯作者：
Salem, Khaled A.
影响因子：
6.6
作者：
Bacon, Constance G.;Mittleman, Murray A.;Rimm, Eric B.
通讯作者：
Rimm, Eric B.