Time-varying effects of income on hippocampal volume trajectories in adolescent girls.
Time-varying effects of income on hippocampal volume trajectories in adolescent girls.
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DOI：
10.1016/j.dcn.2017.12.005
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发表时间：
2018-04
影响因子：
4.7
通讯作者：
Gotlib IH
中科院分区：
文献类型：
--
作者：
Ellwood-Lowe ME;Humphreys KL;Ordaz SJ;Camacho MC;Sacchet MD;Gotlib IH
来自低SES家庭的孩子表现出比高SES家庭的同龄人更小的海马体体积。然而，很少有研究将海马区的发育轨迹作为SES的函数进行比较。因此，尚不清楚最初的等级顺序稳定性是否保持不变，或者在青春期过程中体积是否发散/收敛。在101名年龄在10-24岁的女孩样本中，我们研究了家庭收入与父母教育、SES代用品和海马体体积变化之间的纵向联系。使用MRI获得海马体体积；使用混合建模，我们考察了收入和教育程度对不同年龄的海马体体积的影响。正如预期的那样，在整个开发过程中，音量的变化是非线性的。此外，轨迹在青春期中期出现分歧，低收入女孩表现出海马体体积的减少。与收入相关的差异在18岁时达到最大，此后轨迹趋于一致。当考虑到母亲的海马体体积时，这种交互作用仍然显著，这表明环境对潜在的遗传差异有独特的贡献。相比之下，父母教育和后代海马体体积之间的关联在青春期期间似乎是稳定的，父母教育水平越高，海马体体积就越大。这些发现构成了初步证据，表明来自低收入家庭的女孩表现出独特的海马体发育轨迹，差异在青春期后期最为明显。
Children from lower-SES families exhibit smaller hippocampal volume than do their higher-SES peers. Few studies, however, have compared hippocampal developmental trajectories as a function of SES. Thus, it is unclear whether initial rank-order stability is preserved, or whether volumes diverge/converge over the course of adolescence. In a sample of 101 girls ages 10–24 years, we examined the longitudinal association between family income and parental education, proxies for SES, and changes in hippocampal volume. Hippocampal volume was obtained using MRI; using mixed modeling, we examined the effects of income and education on hippocampal volume across age. As expected, changes in volume were non-linear across development. Further, trajectories diverged in mid-adolescence, with lower-income girls exhibiting reductions in hippocampal volume. Maximal income-related differences were observed at 18 years, and trajectories converged thereafter. This interaction remained significant when accounting for maternal hippocampal volume, suggesting a unique contribution of environment over potential heritable differences. In contrast, the association between parental education and offspring hippocampal volume appeared to be stable across adolescence, with higher levels of parental education predicting consistently larger hippocampal volume. These findings constitute preliminary evidence that girls from lower-income homes exhibit unique trajectories of hippocampal growth, with differences most evident in late adolescence.
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影响因子：
4.6
作者：
Coley, Rebekah Levine;Sims, Jacqueline;Spielvogel, Bryn
通讯作者：
Spielvogel, Bryn
影响因子：
7.6
作者：
Andersen, SL;Teicher, MH
通讯作者：
Teicher, MH
DOI：
10.1177/2372732217721933
发表时间：
2017-01-01
影响因子：
3.8
作者：
Amso, Dima;Lynn, Andrew
通讯作者：
Lynn, Andrew
影响因子：
3.9
作者：
Duncan, Greg J.;Magnuson, Katherine
通讯作者：
Magnuson, Katherine
影响因子：
4.2
作者：
Butterworth, Peter;Cherbuin, Nicolas;Anstey, Kaarin J.
通讯作者：
Anstey, Kaarin J.