Immunomodulatory effects of phytogenics in chickens and pigs - A review.
Immunomodulatory effects of phytogenics in chickens and pigs - A review.
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DOI：
10.5713/ajas.17.0657
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发表时间：
2018-05
期刊：
影响因子：
--
通讯作者：
Lee TT
中科院分区：
文献类型：
--
作者：
Huang CM;Lee TT
环境应激源如病原体和毒素可通过侵入胃肠道（GIT）来抑制动物免疫系统，在那里它们可损害性能和生产，以及导致死亡率增加。因此，保护胃肠道和改善动物健康是动物生产的首要任务。植物化学物质是一种天然物质，具有抗炎、抗真菌、抗病毒和抗氧化等多种功能，是潜在的饲料添加剂。本文重点介绍了香芹酚、肉桂醛、姜黄素和百里酚等植物化学物质对动物免疫相关生理参数的调节作用;许多研究已经证明这些植物化学物质可以提高动物的生产性能和产量。在分子水平上，还研究了炎症基因表达对潜在机制的影响，以及环境刺激和植物化学物质在启动核因子κ B和促分裂原活化蛋白激酶信号通路和改善健康状况方面的作用。
Environmental stressors like pathogens and toxins may depress the animal immune system through invasion of the gastrointestinal tract (GIT) tract, where they may impair performance and production, as well as lead to increased mortality rates. Therefore, protection of the GIT tract and improving animal health are top priorities in animal production. Being natural-sourced materials, phytochemicals are potential feed additives possessing multiple functions, including: anti-inflammatory, anti-fungal, anti-viral and antioxidative properties. This paper focuses on immunity-related physiological parameters regulated by phytochemicals, such as carvacrol, cinnamaldehyde, curcumin, and thymol; many studies have proven that these phytochemicals can improve animal performance and production. On the molecular level, the impact of inflammatory gene expression on underlying mechanisms was also examined, as were the effects of environmental stimuli and phytochemicals in initiating nuclear factor kappa B and mitogen-activated protein kinases signaling pathways and improving health conditions.
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影响因子：
2.9
作者：
Genovesea, Kenneth J.;He, Haiqi;Kogut, Michael H.
通讯作者：
Kogut, Michael H.
影响因子：
2.1
作者：
Gessner DK;Fiesel A;Most E;Dinges J;Wen G;Ringseis R;Eder K
通讯作者：
Eder K
影响因子：
3.7
作者：
Ghareeb K;Awad WA;Soodoi C;Sasgary S;Strasser A;Böhm J
通讯作者：
Böhm J
影响因子：
4.4
作者：
Burkholder, K. M.;Thompson, K. L.;Patterson, J. A.
通讯作者：
Patterson, J. A.
DOI：
10.1016/0960-0760(91)90284-c
发表时间：
1991-01-01
影响因子：
4.1
作者：
BESEDOVSKY, HO;DELREY, A;KABIERSCH, A
通讯作者：
KABIERSCH, A