Anatomical inputs to sulcal portions of areas 9m and 8Bm in the macaque monkey.
Anatomical inputs to sulcal portions of areas 9m and 8Bm in the macaque monkey.
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DOI：
10.3389/fnana.2015.00030
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发表时间：
2015
影响因子：
2.9
通讯作者：
Ichinohe N
中科院分区：
文献类型：
--
作者：
Eradath MK;Abe H;Matsumoto M;Matsumoto K;Tanaka K;Ichinohe N
从前扣带沟背侧记录到的神经元活动表明，该皮质区参与控制搜索与重复、基于目标的动作选择和关于动作值的预测误差的编码。在这项研究中，为了探索这些神经元活动的潜在解剖学基础，我们将逆行示踪剂(CTB-Alexa-488和CTB-Gold)注入前扣带沟背侧，并观察了标记细胞体在猕猴脑中的分布。尼氏染色显示扣带前沟背侧皮质有一致的第4层，表明该皮质区是颗粒状前额叶皮质的一部分。注射部位位于9M区沟部2例，8Bm区沟部1例。除注射部位周围两个区(9M区和8Bm区)连续分布有标记细胞外，所有病例的标记细胞均密集分布在扣带区(24区、32区和23区)。两例注射至9M区的前额叶其他区(46、10、11、12区)也有密集的标记细胞，而注射到8Bm区的沟部的2例则在运动前区(F6、F7)有密集的标记细胞。前额叶和运动前区细胞的密集标记与以前在9区和8B区背部注射后发现的更相似。所有病例的标记细胞均分布于丘脑内侧背核、屏状核和黑质致密部。
Neuronal activities recorded from the dorsal bank of the anterior cingulate sulcus have suggested that this cortical area is involved in control of search vs. repetition, goal-based action selection and encoding of prediction error regarding action value. In this study, to explore potential anatomical bases for these neuronal activities, we injected retrograde tracers (CTB-Alexa-488 and CTB-gold) into the dorsal bank of the anterior cingulate sulcus and examined the distribution of labeled cell bodies in macaque monkey brains. The Nissl staining showed that the cortex in the dorsal bank of the anterior cingulate sulcus has consistent layer 4 which means that the cortical region is a part of the granular prefrontal cortex. The injection site belonged to the sulcal portion of area 9m in two cases and the sulcal portion of area 8Bm in one case. In addition to the continuous distribution of labeled cells in the two areas (areas 9m and 8Bm) around the injection site, the labeled cells were densely distributed in the cingulate areas (areas 24, 32, and 23) in all the cases. The dense labeling of cells was also found in other prefrontal areas (areas 46, 10, 11, and 12) in the two cases with injection into the sulcal portion of area 9m, whereas the dense labeling of cells was found in pre-motor areas (F6 and F7) in the case with injection into the sulcal portion of area 8Bm. The dense labeling of cells in the prefrontal and premotor areas was more similar to those previously found after injections into dorsal parts of areas 9 and 8B. Subcortical distribution of labeled cells was found in the mediodorsal nucleus of thalamus, claustrum, and substantia nigra pars compacta in all the cases.
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DOI：
10.1093/cercor/bhs270
发表时间：
2014-01
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Markov NT;Ercsey-Ravasz MM;Ribeiro Gomes AR;Lamy C;Magrou L;Vezoli J;Misery P;Falchier A;Quilodran R;Gariel MA;Sallet J;Gamanut R;Huissoud C;Clavagnier S;Giroud P;Sappey-Marinier D;Barone P;Dehay C;Toroczkai Z;Knoblauch K;Van Essen DC;Kennedy H
通讯作者：
Kennedy H
影响因子：
2.9
作者：
Matsumoto, Madoka;Matsumoto, Kenji;Tanaka, Keiji
通讯作者：
Tanaka, Keiji
影响因子：
6
作者：
Barbas, H;Hilgetag, CC
通讯作者：
Hilgetag, CC
影响因子：
2.9
作者：
ARIKUNI, T;SAKO, H;MURATA, A
通讯作者：
MURATA, A
影响因子：
2.5
作者：
LUPPINO, G;MATELLI, M;RIZZOLATTI, G
通讯作者：
RIZZOLATTI, G