Decoding the role of the cerebellum in the early stages of reading acquisition.
Decoding the role of the cerebellum in the early stages of reading acquisition.
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DOI：
10.1016/j.cortex.2021.02.033
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发表时间：
2021-08
期刊：
影响因子：
--
通讯作者：
Hoeft F
中科院分区：
文献类型：
--
作者：
Li H;Kepinska O;Caballero JN;Zekelman L;Marks RA;Uchikoshi Y;Kovelman I;Hoeft F
许多研究一致地报道了在阅读任务中小脑的功能激活，特别是在右小脑半球。然而，目前还不清楚这些区域（或哪个区域）是否在阅读习得的最早阶段也参与了阅读。在这里，我们调查是否以及如何小脑有助于阅读收购。我们测试了80名5-6岁的儿童，他们进行了视觉单词匹配任务，在此期间收集了功能性MRI（fMRI）数据。我们发现双侧小脑半球在视觉文字处理过程中被显著激活。此外，激活左侧小脑小叶VII延伸到小叶VIII负相关和显着与当前的阅读能力，而激活右侧小脑小叶VII延伸到小叶VIII显着和正相关与未来的阅读能力。通过功能连接模式的功能解码进一步揭示了左右小脑小叶与不同的大脑皮层连接。我们的研究结果表明，劳动分工之间的左，右小脑小叶开始读者。
Numerous studies have consistently reported functional activation of the cerebellum during reading tasks, especially in the right cerebellar hemisphere. However, it remains unclear whether these regions (or which region) are also involved in reading in the earliest stages of reading acquisition. Here, we investigated whether and how the cerebellum contributes to reading acquisition. We tested 80 5–6-year-old kindergarteners, who performed a visual word matching task during which functional MRI (fMRI) data were collected. We found that bilateral cerebellar hemispheres were significantly activated during visual word processing. Moreover, activation of left cerebellar lobule VII extended to lobule VIII negatively and significantly correlated with current reading ability, whereas activation of right cerebellar lobule VII extended to lobule VIII significantly and positively correlated with future reading ability. Functional decoding via functional connectivity patterns further revealed that left and right cerebellar lobules connected with different cerebral cortex. Our results suggest a division of labor between the left and right cerebellar lobules in beginning readers.
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