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Chemical Biology of Amanitin-Induced Transcriptional Inhibiton

Chemical Biology of Amanitin-Induced Transcriptional Inhibiton
鹅膏蕈碱诱导的转录抑制的化学生物学
批准号:
200529
负责人:
Perrin David M
金额:
$26.07万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2014-03-01

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中文摘要
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英文摘要
Most chemotherapeutics act by associating with DNA which is being copied into messenger RNA by the cellular machinery - a process known as transcription. RNA polymerase is a multi-component protein machine that is physically bound to (touching) the DNA a
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Synthetic amatoxins for applications in targeted therapy and molecular pharmacology
  • 批准号:
    468969
  • 项目类别:
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  • 资助金额:
    $77.47万
  • 财政年份:
    2022
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COVID-19 Variant Supplement - Peptide macrocycle decoys against COVID-19 viral spike protein
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    443199
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  • 财政年份:
    2021
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    Perrin David M
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Peptide macrocycle decoys against COVID-19 viral spike protein
  • 批准号:
    429721
  • 项目类别:
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  • 资助金额:
    $12.17万
  • 财政年份:
    2020
  • 负责人:
    Perrin David M
  • 依托单位:
Alpha-amanitin: synthetic derivatives for applications in targeted therapy
  • 批准号:
    371282
  • 项目类别:
    Operating Grants
  • 资助金额:
    $29.54万
  • 财政年份:
    2017
  • 负责人:
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  • 依托单位:
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