Innovative green technology for bio-particle engineering

生物粒子工程的创新绿色技术

• 批准号: DP1096019
• 负责人: Em/Prof Neil Foster
• 金额: $ 28.91万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-02-14 至 2013-05-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1096019
• 关键词: Innovative; green; technology; bio; particle

Approximately 40% of new pharmaceuticals are poorly soluble in bodily fluids. In many cases this leads to poor bioavailability, and consequent undesirable side effects as a result of high compensating dosages and generally poor patient compliance. These issues will be addressed by developing a green technology for the re-engineering of pharmaceuticals with the objective of increasing bioavilability. The research programme falls within the Designated Research Priority of Frontier Technologies for Building and Transforming Australian Industries.

大约40%的新药在体液中溶解度很差。在许多情况下，这导致较差的生物利用度，以及由于高补偿剂量和通常较差的患者依从性而导致的不期望的副作用。 这些问题将通过开发一种绿色技术来解决，以提高生物利用度为目标，重新设计药物。该研究计划属于福尔斯指定的前沿技术的研究优先建设和改造澳大利亚产业。