The role of the WAVE regulatory complex in commissural axon guidance

WAVE 调节复合物在连合轴突引导中的作用

• 批准号: 453295
• 负责人: Charron Frederic
• 金额: $ 72.45万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-09-01 至 2026-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=453295&lang=en
• 关键词: Axon Guidance; Boc; Commissural Neurons; Cytoskeleton; Dcc; Growth Cone; Netrin; Sonic Hedgehog; Spinal Cord

This proposal focuses on the role of Sonic hedgehog (Shh) and Netrin-1 in the formation of the nervous system. In particular, we are interested in how Shh and Netrin-1 help direct neurons such that they form the proper connections during nervous system de

该提案重点关注 Sonic Hedgehog (Shh) 和 Netrin-1 在神经系统形成中的作用。我们特别感兴趣的是 Shh 和 Netrin-1 如何帮助指导神经元，使其在神经系统发育过程中形成正确的连接。