Unravelling the brain circuits linking emotions and heart rate variability.

解开连接情绪和心率变异性的大脑回路。

• 批准号: DP230103058
• 负责人: Prof Andrew Allen
• 金额: $ 66.58万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230103058
• 关键词: Unravelling; brain; circuits; linking; emotions

We are all familiar with the rapid breathing and heart pounding that occurs when we are frightened. Is the feeling of panic because we sense our heart pounding, or does our heart pound because we panic? This age-old question has resisted attempts to understand its neurobiological basis. This project aims to address this lack of knowledge using novel cutting-edge neuroscience methods that enable mapping of connected brain pathways and the ability to change the activity of specific brain cells with millisecond time resolution. The project will identify, and functionally characterise, the link between the heart and emotions, to gain new insights into the interaction between the autonomic nervous system and disordered emotional regulation.

我们都熟悉当我们害怕时会出现的呼吸急促和心跳加速。恐慌感是因为我们感觉到自己的心脏在跳动，还是因为我们感到惊慌？这个由来已久的问题拒绝了理解其神经生物学基础的尝试。该项目旨在利用新的尖端神经科学方法解决这一知识缺乏的问题，这些方法能够绘制相互连接的大脑路径图，并能够以毫秒的时间分辨率改变特定脑细胞的活动。该项目将确定心脏和情绪之间的联系，并从功能上描述它们之间的联系，以获得对自主神经系统和紊乱的情绪调节之间相互作用的新见解。