Central neural circuits subserving nutrient–activated thermogenesis - the basis of post prandial energy expenditure

中枢神经回路促进营养激活产热——餐后能量消耗的基础

• 批准号: nhmrc : 1145144
• 负责人: Prof Andrew Allen
• 金额: $ 51.81万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/central-neural-circuits-energy-expenditure/1320370
• 关键词: Central; neural; circuits; subserving; nutrient

Studies of “energy burning” brown fat, including its importance in the determination of obesity in humans and the potential to increase its capacity by turning white fat into brown-like fat are currently foremost in obesity research. Here we study the detail of brain pathways that dictate brown fat activity after a meal resulting in the burning of ingested calories and reduction of body weight. The results will give us a better idea of how we can harness brown fat to combat obesity.

“燃烧能量”棕色脂肪的研究，包括它在确定人类肥胖方面的重要性，以及通过将白色脂肪转变为棕色脂肪来增加其能力的可能性，目前是肥胖症研究的首要内容。在这里，我们研究大脑通路的细节，这些通路规定了饭后棕色脂肪的活动，从而燃烧摄入的卡路里和减轻体重。这一结果将让我们更好地了解如何利用棕色脂肪来对抗肥胖。