Organic and Organometallic Chemistry

无机、生物无机和有机金属项目资助与有机分子和过渡金属配合物反应相关的基础化学研究。该领域的研究将提供金属和有机物之间反应途径的知识，这将在表面科学，材料科学和多相催化等领域具有重要意义。该项目的目标是发展有机分子和过渡金属配合物之间反应的详细机理理解。该项目的一个重点是金属介导的碳-碳和碳氢键的形成，因为这些过程是从简单碳框架构建复杂碳框架的核心。此外，重点将放在与碳-氮和碳-氧键形成有关的有机金属反应上，因为目前对这些转变知之甚少。该项目还涉及合作研究，旨在加强对反应机制的理解，并探索有机金属化学可能产生影响的新领域。这些实验旨在研究有机金属反应的热力学，测量协调不饱和和顺磁性中间体的快速反应速率，将定向金属基分子附着在电极上，并研究利用金属配合物结合抗体作为具有高特异性催化剂的可能性。

The Inorganic, Bioinorganic, and Organometallic Program funds research which explores the fundamental chemistry associated with reactions involving organic molecules and transition metal complexes. Research in this area will provide knowledge of reaction pathways between metals and organics which will be important in areas such as surface science, material science and heterogeneous catalysis. The goal of this project is the development of detailed mechanistic understanding of reactions between organic molecules and transition metal complexes. One focus of this project is the metal-mediated formation of carbon-carbon and carbon-hydrogen bonds, since such processes are central to the construction of complex carbon frameworks from simple ones. In addition, emphasis will be placed on organometallic reactions that are involved in the formation of carbon-nitrogen and carbon-oxygen bonds, as substantially less is known at present about these transformations. The project also involves collaborative studies designed to enhance understanding of reaction mechanisms and explore new areas in which organometallic chemistry might have an impact. These include experiments designed to study the thermodynamics of organometallic reactions, measure the rapid rates of reaction of coordinatively unsaturated and paramagnetic intermediates, attach oriented metal-based molecules to electrodes, and examine the possibility of utilizing metal complexes bound to antibodies as catalysts having high specificities.