Organic and Organometallic Chemistry

有机和有机金属化学

• 批准号: 8722801
• 负责人: Robert Bergman
• 金额: $ 59.17万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-05-01 至 1992-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8722801&HistoricalAwards=false
• 关键词: Organic; Organometallic; Chemistry

The Inorganic, Bioinorganic, and Organometallic Program funds research which explores the fundamental chemistry associated with reactions involving organic molecules and transition metal complexes. Research in this area will provide knowledge of reaction pathways between metals and organics which will be important in areas such as surface science, material science and heterogeneous catalysis. The goal of this project is the development of detailed mechanistic understanding of reactions between organic molecules and transition metal complexes. One focus of this project is the metal-mediated formation of carbon-carbon and carbon-hydrogen bonds, since such processes are central to the construction of complex carbon frameworks from simple ones. In addition, emphasis will be placed on organometallic reactions that are involved in the formation of carbon-nitrogen and carbon-oxygen bonds, as substantially less is known at present about these transformations. The project also involves collaborative studies designed to enhance understanding of reaction mechanisms and explore new areas in which organometallic chemistry might have an impact. These include experiments designed to study the thermodynamics of organometallic reactions, measure the rapid rates of reaction of coordinatively unsaturated and paramagnetic intermediates, attach oriented metal-based molecules to electrodes, and examine the possibility of utilizing metal complexes bound to antibodies as catalysts having high specificities.

无机，生物无机和有机物计划基金 研究探索基础化学相关的 涉及有机分子和过渡金属的反应 配合物 该领域的研究将提供以下知识： 金属和有机物之间的反应途径， 在表面科学、材料科学、 和多相催化。 该项目的目标是开发详细的 有机物之间反应的机械理解 分子和过渡金属络合物。其中一个焦点是 项目是金属介导的碳-碳形成， 碳-氢键，因为这样的过程是核心的 从简单的碳结构构建复杂的碳结构。 在 此外，重点将放在有机金属反应 参与了碳氮的形成 碳-氧键，因为目前已知的少得多 关于这些转变。 该项目还涉及 合作研究，旨在提高对 反应机制，并探索新的领域， 有机金属化学可能会产生影响。 这些包括 实验旨在研究热力学 有机金属反应，测量反应的快速速率 配位不饱和和顺磁性中间体， 将定向的金属基分子附着到电极上，以及 研究利用金属络合物结合到 作为催化剂的抗体具有高特异性。