Organic and Organometallic Chemistry

有机和有机金属化学

• 批准号: 0094349
• 负责人: Robert Bergman
• 金额: $ 66.3万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2005-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0094349&HistoricalAwards=false
• 关键词: Organic; Organometallic; Chemistry

Dr. Robert G. Bergman, Chemistry Department, University of California at Berkeley is supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program of the Chemistry Division for studies of organometallic reaction mechanisms in homogeneous solution. Efforts will be focused on three projects. The first is a systematic development of the synthesis of late-metal-heteroatom complexes and studies of the mechanisms of the reactions of these compounds with organic substances. Fundamental chemistry of metal-oxygen and -nitrogen single bonds, hydrogen/heteroatom transfer reactions, and the basicity of the electronegative atom in metal-heteroatom complexes are among the topics to be investigated. The second section is a detailed study of the rhodium catalyzed hydroformylation of epoxides. The hydroformylation of other three member ring systems will be included with hopes of developing new, convenient routes to a variety of useful organic products. Thirdly, the reactions of organometallic compounds with free atoms and metastable diatomics will be investigated. The emphasis will be on species that have opened new pathways in organic chemistry, but have not been much applied to organometallic systems. Chemical reactions involving organic molecules and transition metal complexes are fundamental to the understanding of important catalytic and biological processes. This research will expand the fundamental chemical understanding of metal-organic interactions, be applied to more complicated systems, and aid the development of new practical applications in synthetic and catalytic chemistry.

Robert G.博士伯格曼，化学系，大学 加州伯克利分校是由无机，生物无机和有机化学计划的化学部的研究有机金属反应机制在均相溶液。 工作重点将放在三个项目上。 第一个是后金属-杂原子配合物的合成的系统发展和这些化合物与有机物质的反应机理的研究。金属-氧和-氮单键的基础化学，氢/杂原子转移反应，以及金属-杂原子络合物中的电负性原子的碱性是待研究的主题之一。第二部分详细研究了铑催化的环氧化物加氢反应。其他三元环体系的加氢反应也将包括在内，希望能开发出各种有用的有机产品的新的、方便的路线。第三，研究了金属有机化合物与自由原子和亚稳态化合物的反应。重点将放在那些在有机化学中开辟了新途径，但还没有太多应用于有机金属体系的物种上。涉及有机分子和过渡金属络合物的化学反应是理解重要催化和生物过程的基础。 这项研究将扩大对金属-有机相互作用的基本化学理解，应用于更复杂的系统，并有助于在合成和催化化学中开发新的实际应用。