Organic and Organometallic Chemistry

该奖项在无机，生物无机和有机化学 该计划继续支持罗伯特·G博士的工作伯格曼 加州大学伯克利分校化学系， 有机分子与过渡金属配合物的反应。 一个领域 研究的重点是合成含两种金属的新配合物 彼此靠近。 具体目标是 由于存在两种金属， 具有非常不同的电子特性，或者存在不同的 在每个金属中心的反应性配体。 对这些材料的研究将 专注于适用于化学利用的反应， 小有机分子，如烯烃、炔烃和二氧化碳，以及 有机合成中重要的转化类型，例如 碳-碳或碳-杂原子键形成。 的第二区域 研究是生成有机金属物种， 由于在金属中心存在未成对电子而具有反应性， 即有机金属自由基，并能够形成 与金属形成相对较强的共价键。 此外， 从相对非酸性的金属氧化物中提取质子将是 开发，以产生非常亲核，低价阴离子 金属配合物 我们对发生在有机溶剂中的有机金属反应有很多了解。 偶电子络合物含有一个金属中心， 可接近的电荷和氧化态。这个项目超越了这些 调查领域，以了解反应细节， 涉及奇数电子的情况，不常见的金属氧化 或者不止一个金属中心。 结果会增加 了解与化学制造相关的反应

This award in the Inorganic, Bioinorganic, and Organometallic Chemistry Program provides continued support to work by Dr. Robert G. Bergman of the Chemistry Department, University of California at Berkeley, on reactions of organic molecules with transition metal complexes. One area of investigation is the synthesis of new complexes containing two metals located in close proximity to one another. Specifically targeted are systems that are unsymmetrical, due to either the presence of two metals with very different electronic properties or to the presence of different reactive ligands at each metal center. Research on these materials will focus on reactions that are applicable to the chemical utilization of small organic molecules, such as alkenes, alkynes and carbon dioxide, and to the type of transformations important in organic synthesis, such as carbon-carbon or carbon-heteroatom bond formation. A second area of investigation is the generation of organometallic species that are highly reactive due to the presence of an unpaired electron at the metal center, that is, organometallic free radicals, and capable of forming a relatively strong covalent bond to the metal. Also, methods for the abstraction of protons from relatively unacidic metal hydrides will be developed in order to generate very nucleophilic, low valent anionic metal complexes. Much is known about organometallic reactions that take place in even-electron complexes that contain a single metal center with easily accessible charges and oxidation states. This project moves beyond these areas of investigation to obtain understanding of reaction details in cases involving an odd-number of electrons, uncommon metal oxidation states, or more than one metal center. The results will increase understanding of reactions which are relevant to chemical manufacturing