Optical Activity Determinations in Chemistry and Biochemistry

化学和生物化学中的旋光度测定

• 批准号: 8750180
• 负责人: Nancy Mills
• 金额: $ 1.45万
• 依托单位: Trinity University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-06-15 至 1989-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8750180&HistoricalAwards=false
• 关键词: Optical; Activity; Determinations; Chemistry; Biochemistry

Spectropolarimetry is being fully integrated into the undergraduate chemistry curriculum at Trinity University. A polarimeter equipped with a monochrometer and continuous sources affords applications that demonstrate the essential characteristics of optical activity measurements in understanding the 3-dimensional structure of chiral molecules. Determination of the optical rotations of inorganic complexes and organic compounds, the measurement of optical rotatory dispersion curves in conformational analyses and base stacking of nucleosides, and the determination of the specific rotation of pure enantiomers by modern methods are among the activities students are experiencing.

Spectropolarimetry已完全集成到Trinity University的本科化学课程中。配备了单色计和连续源的偏振仪提供了一种应用，以证明光活性测量的基本特征在理解手性分子的三维结构时。确定无机络合物和有机化合物的光旋，在构象分析和核苷的基础堆积中测量光旋转分散曲线的测量以及通过现代方法确定纯对映异构体的特定旋转是学生在这些活动中经历的。