Optical Activity Determinations in Chemistry and Biochemistry

化学和生物化学中的旋光度测定

• 批准号: 8750180
• 负责人: Nancy Mills
• 金额: $ 1.45万
• 依托单位: Trinity University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-06-15 至 1989-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8750180&HistoricalAwards=false
• 关键词: Optical; Activity; Determinations; Chemistry; Biochemistry

Spectropolarimetry is being fully integrated into the undergraduate chemistry curriculum at Trinity University. A polarimeter equipped with a monochrometer and continuous sources affords applications that demonstrate the essential characteristics of optical activity measurements in understanding the 3-dimensional structure of chiral molecules. Determination of the optical rotations of inorganic complexes and organic compounds, the measurement of optical rotatory dispersion curves in conformational analyses and base stacking of nucleosides, and the determination of the specific rotation of pure enantiomers by modern methods are among the activities students are experiencing.

分光光度学正在被完全纳入三一大学的本科生化学课程。配备单色仪和连续光源的旋光仪提供了展示旋光度测量在理解手性分子的三维结构中的基本特征的应用。无机络合物和有机化合物旋光度的测定，核苷构象分析和碱基堆积中旋光色散曲线的测定，以及用现代方法测定纯对映体的比旋光度，都是学生们正在学习的活动。