Establishment of a Regional NMR Site at Trinity University

在三一大学建立区域核磁共振站点

• 批准号: 0126417
• 负责人: Nancy Mills
• 金额: $ 10.37万
• 依托单位: Trinity University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-01 至 2004-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0126417&HistoricalAwards=false
• 关键词: Establishment; Regional; NMR; Site; Trinity

Chemistry (12)With the purchase of a Varian Mercury 300 MHz NMR spectrometer, we have created a regional NMR site by which six two- and four-year colleges and universities in the San Antonio region with no previous access to NMR instrumentation have easy and effective access to one which is housed at and maintained by Trinity University. To overcome the access limitation to use of NMR at a remote site, we have designed a process in which samples from the participating institutions are delivered to Trinity University, are prepared for analysis by a student worker, run automatically with a sample changer, and the data (free induction decays, FID's) downloaded to a Trinity University server. Students at the participating institutions transfer the FID's to a local computer to be processed using free software. Each of the six institutions have thoughtfully chosen a set of experiments from the chemical education literature to use in their curricula. The participating institutions pay only for the time of the student worker and a nominal fee for deuterated solvents. They are therefore able to control and incorporate as much NMR access as they can afford. The pedagogical advantages are several. First, students process their own spectra and learn to make decisions about integration or expansion of the various regions of the spectrum. Second, since the FID is retrievable from a server, they can return to the spectra for reprocessing if necessary. Third, by running spectra on real samples, they have opportunities to deal with impurities and develop greater sophistication in interpretation. Finally, being able to acquire spectra of real samples allow students to identify unknown products of chemical reactions.

化学（12）通过购买瓦里安水星300 MHz核磁共振光谱仪，我们创建了一个区域核磁共振站点，通过该站点，圣安东尼奥地区的六所两年制和四年制学院和大学以前没有使用过核磁共振仪器，现在可以轻松有效地访问位于三一大学并由三一大学维护的核磁共振仪器。为了克服在远程站点使用核磁共振的访问限制，我们设计了一个过程，其中来自参与机构的样品被送到三一大学，由学生工作人员准备分析，使用样品转换器自动运行，数据（自由感应衰减，FID）下载到三一大学的服务器上。参与机构的学生将FID转移到本地电脑上，使用免费软件进行处理。这六所院校都从化学教育文献中精心挑选了一组实验用于他们的课程。参与机构只支付学生工人的时间和氘化溶剂的象征性费用。因此，他们能够控制和整合尽可能多的核磁共振访问，因为他们可以负担得起。教学上的优势有几个。首先，学生处理自己的光谱，并学习如何对光谱的各个区域进行整合或扩展。其次，由于FID可以从服务器上检索到，如果需要的话，它们可以返回到光谱中进行再处理。第三，通过在实际样品上运行光谱，他们有机会处理杂质，并在解释中发展更复杂的技术。最后，能够获得真实样品的光谱，使学生能够识别化学反应的未知产物。