'Micro Sensing Satellite' for Bioreactor Monitoring

用于生物反应器监测的“微传感卫星”

• 批准号: 9011699
• 负责人: Young Lee
• 金额: $ 3万
• 依托单位: Drexel University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-04-01 至 1991-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9011699&HistoricalAwards=false
• 关键词: Micro; Sensing; Satellite; Bioreactor; Monitoring

Biosensors employing enzymes or antibodies are capable of measuring a vast number of simple molecules as well as macromolecules involved in industrial bioprocesses. However, this capability cannot be tapped readily for bioreactor monitoring because enzymes and antibodies lose their activity during steam sterilization. By making use of sterile fabrication methods and remote sensing technology, this proposal seeks to design and fabricate a prototype biosensor which can be used in bioreactors without the steam sterilization requirement.

采用酶或抗体的生物传感器能够 测量大量的简单分子， 涉及工业生物过程的大分子。 然而，这种能力不能轻易地被利用， 生物反应器监测，因为酶和抗体失去 在蒸汽灭菌过程中的活性。 利用 无菌制造方法和遥感 技术，这项建议旨在设计和制造一个 可用于生物反应器的原型生物传感器 无需蒸汽灭菌要求。