A Sensor for Determining Viable Cell Density

活细胞密度是 最重要的参数 发酵过程。 许多 间接测定法 细胞密度已经被引入 在过去。 但这些 方法具有非特异性。 提出了一种传感器， 活细胞的显式测量 培养基中的数量密度。 在所提出的方法中，可行的 细胞区别于其他 惰性粒子通过使用 活细胞的特性。 测量速度为 通过快速计数实现。 的 传感器可用于单一培养物 没有校准。 离线作为 以及在线传感器 构建了

Viable cell density is one of the most important parameters in fermentation processes. Many indirect methods of determining cell density have been introduced in the past. However, these methods suffer for non-specificity. A sensor is proposed for rapid and explicit measurement of viable cell number density in culture media. In the proposed method, viable cells are distinguished from other inert particles by using the characteristics of living cells. The speed in measurement is achieved by fast counting. The sensor is usable in single cultures without calibration. Off-line as well as on-line sensors are to be constructed.