Acquisition of a System for Quantitative Fluorescence Microscopy and Imaging at Florida State University

佛罗里达州立大学购买定量荧光显微镜和成像系统

• 批准号: 9014510
• 负责人: W. Ross Ellington
• 金额: $ 3.69万
• 依托单位: Florida State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-01-01 至 1992-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9014510&HistoricalAwards=false
• 关键词: Acquisition; System; Quantitative; Fluorescence; Microscopy

NSF funds are requested to purchase enhancements to the instrument to facilitate the use of a microscope imaging system by six research groups in the Department of Biological Science. The quantitative fluorescence system will allow the researchers to investigates a variety of new problems including the following: the role of calcium in prolactin secretion by pituitary cells, the regulation of the intracellular pH in molluscan myocytes, the role of calcium fluxes in the regulation of gene expression in Chlamydonas, the distribution and potential compartmentation of key proteins in brush border cells, the dynamics of intrecellular magnesium in muscle fibers and finally the role of intracellular pH in motility in amoeboid cells. The acquisition of the quantitative fluorescence imaging system will have significant impact on these six groups, all of which are externally funded.

NSF资金被要求购买增强的 一种便于使用显微镜成像系统的仪器 由生物科学系的六个研究小组完成。 定量荧光系统将使研究人员 调查各种新问题，包括 以下：钙在催乳素分泌中的作用， 垂体细胞，调节细胞内pH值， 软体动物心肌细胞，钙流在调节中的作用 衣原体基因表达的分布和潜力 刷状缘细胞中关键蛋白的区室化， 肌纤维中细胞内镁的动态变化， 细胞内pH在变形虫细胞运动中的作用。 的 定量荧光成像系统的获得将 对这六个群体都有重大影响， 外部资助。