Stress, Hormones and Behavior

压力会对健康产生长期影响。 个体 因此，制定战略是中肯的， 来适应和应对压力。 事实上，大多数哺乳动物 进化出的行为和神经内分泌机制， 严峻的条件。 下丘脑-垂体-肾上腺轴 被认为是一个示范系统，说明了中央政府 神经系统对压力有反应。 布朗森博士发现了 一群哺乳动物，在澳大利亚的自然种群中， 不改变他们的行为，但继续强调， 死亡是不可避免的。 没有其他哺乳动物 生命终结的压力作为其生命史的正常部分 战略 因此，应激与神经内分泌的联系 这些动物的行为肯定与 为其他哺乳动物所知。 布朗森博士最初的目标是 建立了一个成功的繁殖群体， 美国的 然后他会分离并理解 行为和神经内分泌机制使这个物种 维持正常的，但现在破坏性的行为， 压力的条件。 这是一个戏剧性的鲁棒性， 这些动物的压力和行为之间的关系 真实的希望解剖和了解它的神经内分泌和 神经化学机制 将这些数据与我们目前的 知识是确立原则的有力工具 关于压力和行为的普遍重要性。 使用这种独特的动物模型， 探索行为如何调节免疫系统 发展适应机制来科普急性和慢性 应力

Stress can have long-term consequences on the health of individuals. Therefore, it is pertinent to develop strategies for adapting and reacting to stress. Indeed, most mammals have evolved behavioral and neuroendocrine mechanisms to cope under severe conditions. The hypothalamic-pituitary-adrenal axis is regarded as a model system illustrating the way the central nervous system responds to stress. Dr. Bronson has identified a group of mammals, in a natural population in Australia, that do not change their behavior but continue to be stressed to the point that death is inevitable. No other mammal incorporates life-terminating stress as a normal part of its life history strategy. Therefore, the neuroendocrine linkages between stress and behavior in these animals must differ sharply from those known for other mammals. Dr. Bronson's initial goal is to establish a successful breeding colony of these unique animals in the United States. He will then isolate and understand the behavioral and neuroendocrine mechanisms that allow this species to maintain normal, but now destructive behavior, under conditions of stress. The dramatic robustness of the relationship between stress and behavior in these animals offers real hope of dissecting and understanding its neuroendocrine and neurochemical mechanisms. Comparing these data with our present knowledge constitutes a powerful tool for establishing principles about stress and behavioral that are universally important. Working with this unique animal model could prove important for exploring the way behavior can modulate the immune system as well as developing adaptive mechanisms to cope with acute and chronic stress.