Studies of Cyclodextrin Chemistry

这个项目是在分析和表面化学的一般领域和荧光光谱的子领域。在这项资助的任期内，华纳教授和他的学生将使用一套光谱方法研究环糊精和一系列多环芳烃（PAHs）之间的相互作用。本研究将采用红外光谱、圆二色光谱、x射线晶体学和荧光光谱来阐明环糊精与多环芳烃之间络合的分子细节，以及在这些体系中加入醇所产生的三元效应。这些调查继续由埃默里大学的华纳教授在美国国家科学基金会的资助下发起的工作。本研究结果将对天然手性化合物和诱导手性化合物的分析方法的发展有一定的指导意义。

This project is in the general area of analytical and surface chemistry and in the subfield of fluorescence spectroscopy. During the tenure of this grant, Professor Warner and his students will examine interactions between cyclodextrins and a series of polycyclic aromatic hydrocarbons (PAHs) using a suite of spectroscopic methods. %%% This research will employ infrared spectroscopy, circular dichroism spectroscopy, x-ray crystallography, and fluorescence spectroscopy to elucidate the molecular details of complexation between cyclodextrins and PAHs together with the ternary effects arising from the addition of alcohols to these systems. These investigations continue work initiated by Professor Warner at Emory University under NSF grant CHE-9001412. The results of this research will be useful in the development of analytical methods for naturally chiral compounds and for compounds with induced chirality.