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Analytical Studies Using Ionic Liquids, GUMBOS, and nanoGUMBOS

使用离子液体、GUMBOS 和 nanoGUMBOS 进行分析研究

基本信息

批准号：
1905105
负责人：
Isiah Warner
金额：
$ 36万
依托单位：
Louisiana State University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-15 至 2023-01-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1905105&HistoricalAwards=false
关键词：
Analytical Studies Using Ionic Liquids

项目摘要

With support from the Chemical Measurement and Imaging Program in the Division of Chemistry, Professors Isiah Warner, Jin-Woo Choi, and Kevin McCarter and their groups at Louisiana State University are using liquid and solid organic salts as the basis for new kinds of chemical sensors for important and biomedically relevant analytes. These solid phase salts are being formulated as nanomaterials to enable additional analytical applications. The probe involves coupling the salts with a "quartz crystal microbalance" (QCM) - an instrument normally used for simply weighing minute amounts of materials, but in this case providing selective sensing based on the selective interactions of the salts with target analytes. Miniature versions of this novel instrumentation are being developed to enable use as portable sensors for analyses of volatile analytes. The work exposes a diverse group of students to state-of-the-art research in chemical instrumentation through research opportunities and extensive public outreach.These studies focus on ionic liquids and solid-state materials derived from a "Group of Uniform Materials Based on Organic Salts" (GUMBOS), including nanomaterials derived from GUMBOS (nanoGUMBOS). The nanoGUMBOS can be safe and effective alternatives relative to many current nanomaterials used for bioanalytical applications. The work targets novel, useful, and environmentally friendly analytical applications. For example, strategies are being developed for selective measurement of analytically important biomedical targets through novel solvent and solid phase extractions. In combination with the QCM, the GUMBOs can serve in sensors using multiple analytical strategies. Novel QCM micro-instrumentation is being developed to enhance the range of analytical applications for this methodology.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在化学系化学测量和成像计划的支持下，路易斯安那州立大学的Isiah Warner、Jin-Woo Choi和Kevin McCarter教授及其团队正在使用液体和固体有机盐作为新型化学传感器的基础，用于重要的和生物医学相关的分析。这些固相盐正被配制成纳米材料，以实现更多的分析应用。探头包括将盐类与“石英晶体微天平”(QCM)耦合，这是一种通常用于简单称量微量物质的仪器，但在这种情况下，根据盐类与目标分析物的选择性相互作用提供选择性传感。这种新型仪器的微型版本正在开发中，以便能够用作分析挥发性分析物的便携式传感器。这项工作通过研究机会和广泛的公共活动使不同的学生群体接触到最先进的化学仪器研究。这些研究重点是离子液体和源自一组基于有机盐的均匀材料(GUMBOS)的固态材料，包括来自GUMBOS的纳米材料(NanGUMBOS)。相对于目前用于生物分析应用的许多纳米材料，纳米GUMBOS是一种安全和有效的替代品。这项工作的目标是新颖、有用和环保的分析应用。例如，正在制定战略，通过新的溶剂和固相萃取选择性地测量具有分析重要性的生物医学目标。与QCM相结合，GUMBOS可用于使用多种分析策略的传感器。正在开发新的QCM微型仪器，以增强该方法的分析应用范围。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

期刊论文数量（14）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Quartz Crystal Microbalance Based Sensor Arrays for Detection and Discrimination of VOCs Using Phosphonium Ionic Liquid Composites.

基于石英晶体微天平的传感器阵列，用于使用鏻离子液体复合材料检测和辨别 VOC。

DOI：
10.3390/s20030615
发表时间：
2020
期刊：
Sensors (Basel, Switzerland)
影响因子：
0
作者：
Vaughan,StephanieR;Pérez,RocíoL;Chhotaray,Pratap;Warner,IsiahM
通讯作者：
Warner,IsiahM

Comparison of Chemotherapeutic Activities of Rhodamine-Based GUMBOS and NanoGUMBOS

DOI：
10.3390/molecules25143272
发表时间：
2020-07-01
期刊：
MOLECULES
影响因子：
4.6
作者：
Bhattarai, Nimisha;Chen, Mi;Warner, Isiah M.
通讯作者：
Warner, Isiah M.

Efficient Photoinduced Energy Transfer in Porphyrin-Based Nanomaterials

DOI：
10.1021/acs.jpcc.0c08985
发表时间：
2020-10
期刊：
Journal of Physical Chemistry C
影响因子：
3.7
作者：
Tony E. Karam;Noureen Siraj;Jeewan C Ranasinghe;P. Kolic;Bishnu P. Regmi;I. Warner;L. Haber
通讯作者：
Tony E. Karam;Noureen Siraj;Jeewan C Ranasinghe;P. Kolic;Bishnu P. Regmi;I. Warner;L. Haber

Protein Discrimination Using a Fluorescence-Based Sensor Array of Thiacarbocyanine-GUMBOS