Replacement of Console and Reverse-Detection Probe for XL-300 NMR Spectrometer

9319666阿克曼这个奖项从化学研究仪器和设施计划将协助化学系在华盛顿大学购买一个现代化的更换控制台和反向检测探头为现有的300兆赫多核核磁共振波谱仪。 该设备将用于以下研究领域：（1）用于控制基因表达的合成核酶、水解化学核酸酶和催化反义试剂;（2）扩展有机化学和高活性中间体的研究，极快反应的前线轨道控制，Germylene的气相重排，Stannylene的新路线，以及三重态亚甲硅烷基、亚锗烷基和亚锡烷基的分子设计;（3）芳香族金属杂环的合成和反应性;以及（4）液相材料加工。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具。 它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于从事前沿研究的化学家来说，使用最先进的NMR光谱分析技术是必不可少的。

9319666 Ackerman This award from the Chemistry Research Instrumentation and Facilities Program will assist the Department of Chemistry at Washington University in the purchase of a modern replacement console and reverse-detection probe for an existing 300 MHz multinuclear NMR Spectrometer. This equipment will be used in the following areas of research: (1) Synthetic Ribozymes, Hydrolytic Chemical Nucleases, and Catalytic Antisense Agents for the Control of Gene Expression; (2) Extended Organic Chemistry and the Study of Highly Reactive Intermediates, Frontier Orbital Control of Very Fast Reactions, Gas-Phase Rearrangements of Germylenes, New Routes to Stannylenes, and the Molecular Design of Triplet Silylenes, Germylenes, and Stannylenes; (3) Synthesis and Reactivity of Aromatic Metallacycles; and (4) Solution-Phase Materials Processing. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research.