Replacement of Console and Reverse-Detection Probe for XL-300 NMR Spectrometer

这份来自化学研究仪器和设施项目的合同将帮助华盛顿大学化学系为现有的300 MHz多核核磁共振光谱仪购买现代替代控制台和反向探测探头。该设备将用于以下研究领域：(1)用于控制基因表达的合成核酶、水解化学核酸酶和催化反义剂；(2)扩展有机化学与高活性中间体的研究，快速反应前沿轨道控制，锗烯的气相重排，合成锡烯的新途径，三联态硅烯、锗烯和锡烯的分子设计；(3)芳香族金属环的合成及反应性研究；(4)液相材料加工。核磁共振（NMR）波谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱是必不可少的化学家谁正在进行前沿研究。

9319666 Ackerman This award from the Chemistry Research Instrumentation and Facilities Program will assist the Department of Chemistry at Washington University in the purchase of a modern replacement console and reverse-detection probe for an existing 300 MHz multinuclear NMR Spectrometer. This equipment will be used in the following areas of research: (1) Synthetic Ribozymes, Hydrolytic Chemical Nucleases, and Catalytic Antisense Agents for the Control of Gene Expression; (2) Extended Organic Chemistry and the Study of Highly Reactive Intermediates, Frontier Orbital Control of Very Fast Reactions, Gas-Phase Rearrangements of Germylenes, New Routes to Stannylenes, and the Molecular Design of Triplet Silylenes, Germylenes, and Stannylenes; (3) Synthesis and Reactivity of Aromatic Metallacycles; and (4) Solution-Phase Materials Processing. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research.