FT/ICR/MS: Techinque Development and Non-Biological Applications

来自分析和表面化学计划的这笔赠款将支持马歇尔教授开发两种新技术，包括傅立叶变换离子回旋共振质谱仪，FT/ICR/MS。第一种方法是一种新的二维方法，应该能够在时间上提供串联的MS/MS，以提供对复杂混合物中发生的所有耦合离子-分子反应的即时识别。第二种技术涉及利用红外光谱确定ICR电池中捕获的气相离子的结构。这项研究将扩展马歇尔教授对FT/ICR/MS这一非常强大的方法的广泛研究，该方法用于表征少量材料，这些材料可以根据其质量进行选择和研究。这一领域的进展将使人们能够更好地理解气相中离子和分子之间发生的基本化学。这将改进各种样品类型中痕量污染物的分析方法。

This grant from the Analytical and Surface Chemistry Program will support Professor Marshall's efforts to develop two new techniques involving Fourier transform ion cyclotron resonance mass spectrometry, FT/ICR/MS. The first method is a new two dimensional approach that should give tandem in time MS/MS to provide immediate identification of all the coupled ion-molecule reactions occuring in a complex mixtures. The second technique involves the determination of the structure of gas-phase ions trapped in the ICR cell by using infrared spectroscopy. This research will extend Professor Marshall's extensive investigations of the very powerful method of FT/ICR/MS for the characterization of small amounts of material which can be selected and studied according to their mass. Advances in this area will allow a better understanding of the fundamental chemistry that occurs between ions and molecules in the gas phase. This will allow for improved methods of analysis of trace contaminants in a wide variety of sample types.