FT/ICR/MS: Techinque Development and Non-Biological Applications

分析和表面化学计划的这笔赠款将支持 马歇尔教授致力于开发两种新技术， 傅里叶变换离子回旋共振质谱法。 第一种方法是一种新的二维方法， 及时串联MS/MS，以立即识别所有 发生在复杂混合物中的离子-分子耦合反应。 的 第二种技术涉及气相结构的确定 离子捕获在ICR细胞通过使用红外光谱。 这项研究将扩展马歇尔教授的广泛研究 FT/ICR/MS的非常强大的方法，用于表征 少量的材料，可以选择和研究，根据 他们的质量。 这一领域的进展将有助于更好地了解 发生在离子和分子之间的基本化学反应， 气相的 这将有助于改进痕量分析方法， 各种样品类型中的污染物。

This grant from the Analytical and Surface Chemistry Program will support Professor Marshall's efforts to develop two new techniques involving Fourier transform ion cyclotron resonance mass spectrometry, FT/ICR/MS. The first method is a new two dimensional approach that should give tandem in time MS/MS to provide immediate identification of all the coupled ion-molecule reactions occuring in a complex mixtures. The second technique involves the determination of the structure of gas-phase ions trapped in the ICR cell by using infrared spectroscopy. This research will extend Professor Marshall's extensive investigations of the very powerful method of FT/ICR/MS for the characterization of small amounts of material which can be selected and studied according to their mass. Advances in this area will allow a better understanding of the fundamental chemistry that occurs between ions and molecules in the gas phase. This will allow for improved methods of analysis of trace contaminants in a wide variety of sample types.