Two-Dimensional Polymerizations in Supramolecular Assemblies

9400369奥布莱恩在过去的十年中，介绍了几种方法来制备超分子组装体。 这些组装体中的许多，例如单层、脂质体和多层，是两亲物的二维阵列。 成功的设计和可重复的制备新材料，从这些组件需要一个清晰的理解聚合过程。 NSF-DMR支持的先前研究成功地提供了对超分子快速扩散体系中两亲物线性聚合性质的基本理解。 新的研究将继续进行的特点交联聚合以及聚合在缓慢扩散制度。 本实验室开发的方法将用于表征新设计的双功能分子在二维组件中的交联效率。 将在高于（快速扩散）和低于（缓慢扩散）双层组件的主相变温度的温度下比较双层中的聚合速率和聚合度。 这些研究的结果将被用来设计新的单体聚合的其他超分子，例如dispersed液晶。 超分子组装体的聚合提供了一种有效的手段来改变它们的化学和物理性质，以制备具有生物和材料科学感兴趣的特定性质的新型材料。 迄今为止的研究表明，聚合的超分子组装体可能在诊断、试剂和药物的受控递送、用于光能的有效转导的稳定组装体的设计和制备、表面改性以及用于有机沸石的稳定化中找到实用性。 ***

9400369 O'Brien Several methods to polymerize supramolecular assemblies were introduced in the last decade. Many of these assemblies, e.g. monolayers, liposomes, and multilayers, are two-dimensional arrays of amphiphiles. Success in the design and reproducible preperation of new materials from these assemblies requires a clear understanding of the polymerization processes. The previous studies suppported by NSF-DMR have successfully provided a basic understanding of the nature of linear polymerizations of amphiphiles in the supramolecular fast-diffusion regime. The new research to be carried over will characterize crosslinking polymerizations as well as polymerizations in the slow-diffusion regime. Methods developed in this laboratory will be used to characterize the efficiency of crosslinking in two-dimensional assemblies with newly designed bifunctional molecules. The rate and degree of polymerization in bilayers will be compared at temperatures above (fast diffusion) and below (slow diffusion) the main-phase transition temperature of the bilayer assembly. These results of these studies on bilayers will be used to design new monomers for the polymerization of other supramolecular, e.g. discotic liquid crystals. %%% The polymerization of supramolecular assemblies provides an effective means to modify their chemical and physical properties to prepare novel materials with particular properties of interest to both biological and material sciences. The research to date indicates that polymerized supramolecular assemblies are likely to find utility in diagnostics, in the controlled delivery of reagents and drugs, in the design and preparation of stable assemblies for the efficient transduction of light energy, in surface modification, and for the stabilization of organic zeolites. ***