CellMaps for cell fate decision making systems

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The cell is the fundamental unit exhibiting the hallmarks of life. The cell is also a fantastically intricate and complex system: its behaviour is shaped by molecular networks and processes that regulate cellular physiology, and the response of the cell to its environment. This Laureate Fellowship aims to describe and make sense of this complexity mathematically. At this sub-cellular level stochasticity and complex non-linear feedbacks are all pervasive. Building on recent advances in mathematics, statistics, theoretical physics, and data science will result in mathematical models of cells, CellMaps, that will generate mechanistic insights into the fundamental dynamical processes underlying cell fate decision making and differentiation.