NMR Facility Modernization

核磁共振设施现代化

• 批准号: 9512197
• 负责人: David Lynn
• 金额: $ 67.27万
• 依托单位: University of Chicago
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-08-15 至 1997-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9512197&HistoricalAwards=false
• 关键词: NMR; Facility; Modernization

ABSTRACT Proposal: 9512197 PI: Lynn, D.G. Institution: University of Chicago This award from the Academic Research Infrastructure Program will help the Department of Chemistry at the University of Chicago acquire consoles for a 500 MHz, 300 MHz, and 400 MHz NMR. The research activity to be supported includes: 1. mechanism of protection by heat shock proteins 2. Chameleonic Amphiphilic Peptides 3. the structure and mechanism of nucleic-acid binding proteins (including metal-binding motifs such as Zn fingers) and of nucleic acid 4. basic chemistry of homogeneous catalysis 5. Synthesis, Structures, and Properties of Catenated Group 14 Molecular Frameworks 6. Conformationally Well-Defined Polymers and Micro-phase Separated Block Copolymers Nuclear Magnetic Resonance (NMR) Spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in areas such as polymers and catalysis, and in biology.

摘要 提案：9512197 PI：林恩，D.G. 机构：芝加哥大学 来自学术研究基础设施计划的这一奖项将帮助芝加哥大学化学系获得500 MHz、300 MHz和400 MHz NMR的控制台。 拟支助的研究活动包括： 1. 热休克蛋白的保护机制 2. 变色龙两亲肽 3. 核酸结合蛋白（包括金属结合蛋白）的结构和机制 基序，如锌指）和核酸 4. 均相催化基础化学 5. 链状14族分子骨架的合成、结构和性质 6. 高分子的构象和微相分离嵌段共聚物 核磁共振（NMR）光谱学是化学家用来阐明分子结构的最强大的工具。 它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于从事前沿研究的化学家来说，使用最先进的NMR光谱分析技术是必不可少的。 这些NMR研究的结果在聚合物和催化以及生物学等领域都很有用。