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A novel drug class for the effective treatment of Giardia infections

A novel drug class for the effective treatment of Giardia infections
一种有效治疗贾第鞭毛虫感染的新型药物
批准号:
LP210301109
负责人:
Prof Adam McCluskey
金额:
$20.36万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2023
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2023-12-13 至 2026-12-12

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中文摘要
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英文摘要
Companion animals play a pivotal role in the lifestyle of the average Australian family. The 9 million cats and dogs, residing in >65% of our households, have provided significant health and well-being benefits to owners, especially during COVID. Ensuring pet health is a primary obligation of pet ownership. Giardia infections (Giardia duodenalis, with 94% of infections in dogs identified as Assemblage A) is the most prevalent enteric parasite identified globally in dogs. Infection rates can be as high as 75% in puppies. Current treatments are failing due to poor efficacy, resistance and poor adherence to treatment schedules. We have identified a novel, extremely rapid acting series of compounds capable of single shot eradication of Giardia.
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