Electrodiffusion in lonic Channels Analyzed with the Gummel Iteration

用 Gummel 迭代分析离子通道中的电扩散

• 批准号: 9726338
• 负责人: Robert Eisenberg
• 金额: $ 9.99万
• 依托单位: RUSH UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-01-01 至 1999-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9726338&HistoricalAwards=false
• 关键词: Electrodiffusion; lonic; Channels; Analyzed; Gummel

Abstract This is a Small Grant for Exploratory Research (SGER) award. Dr. Eisenberg and his colleagues propose to use the methods of semiconductor science to analyze electric current flow through ionic channels of known three dimensional structure in biological systems. Ionic channels are protein molecules found in all living cells and are of great technological and scientific importance to both fundamental understanding of biology as well as practical application of biological principles for product development in the fields of health, energy, and environment . This research is based on the concept that the mathematical models used to describe the properties of ionic channels and semiconductors are nearly the same. This project is designed to test that concept.

摘要 这是一个探索性研究（SGER）奖的小补助金。 Eisenberg博士和他的同事们建议使用半导体科学的方法来分析通过生物系统中已知三维结构的离子通道的电流。离子通道是在所有活细胞中发现的蛋白质分子，对于生物学的基本理解以及健康，能源和环境领域产品开发的生物学原理的实际应用具有重要的技术和科学意义。 本研究是基于这样的概念，即用于描述离子通道和半导体性质的数学模型几乎是相同的。本项目旨在测试这一概念。