Structure and Function of the Insect Mushroom Body in Sensory and Motor Integration
昆虫蘑菇体在感觉和运动整合中的结构和功能
基本信息
- 批准号:9726957
- 负责人:
- 金额:$ 29万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:1998
- 资助国家:美国
- 起止时间:1998-05-01 至 2001-04-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The brain of insects contains a prominent pair of centers known as the mushroom bodies. These structures have been implicated in discrimination of odors important for feeding and mating behavior, and the anatomical organization has been suggested to be a repeated arrangement of an essentially simple wiring pattern. More recent studies now suggest that the mushroom bodies play a central role in a much wider variety of functions, including integration of vision and smell, memory of place, and motor control. Along with these disparate functions, the structure of the mushroom bodies may have far more internal partitioning into locally functioning regions. This project uses a combination of anatomy, physiology, and behavior to examine the sensory signals in uniquely identified nerve cells, and the connections of these neurons to further processing pathways. A novel marking method will allow recording from single neurons in behaving insects, and later recovering the location and form of those active individual cells. Using a comparative approach among species representing key evolutionary lineages, these studies will clarify the organizational ground rules of a brain center that has ancient origins. The demonstration of important roles for the mushroom bodies in integrating sensory information leading to behavioral action may suggest some bases for the extraordinary evolutionary and ecological success of the insects. The impact will extend beyond neuroscience into areas of ecology and evolution, and perhaps also to pest control in agriculture.
昆虫的大脑包含一对突出的中心,称为蘑菇体。 这些结构与对进食和交配行为很重要的气味的辨别有关,而解剖学上的组织被认为是一种基本上简单的布线模式的重复排列。 最近的研究表明,蘑菇体在更广泛的功能中发挥着核心作用,包括视觉和嗅觉的整合,位置记忆和运动控制。 沿着这些不同的功能,蘑菇体的结构可能有更多的内部划分成局部功能区域。 该项目使用解剖学,生理学和行为学的组合来检查独特识别的神经细胞中的感觉信号,以及这些神经元与进一步处理途径的连接。 一种新的标记方法将允许记录行为昆虫的单个神经元,然后恢复这些活跃的单个细胞的位置和形式。 这些研究使用代表关键进化谱系的物种之间的比较方法,将澄清具有古老起源的大脑中心的组织基本规则。 蘑菇体在整合感官信息导致行为行动方面的重要作用的展示可能为昆虫非凡的进化和生态成功提供了一些基础。 其影响将超越神经科学,进入生态学和进化领域,或许还将涉及农业害虫控制。
项目成果
期刊论文数量(0)
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Nicholas Strausfeld其他文献
Brain Structure Resolves the Segmental Affinity of Anomalocaridid Appendages
- DOI:
doi:10.1038/nature13486 - 发表时间:
2014 - 期刊:
- 影响因子:
- 作者:
Peiyun cong;Xiaoya Ma;Xianguang Hou;Gregory Edgecombe;Nicholas Strausfeld - 通讯作者:
Nicholas Strausfeld
Nicholas Strausfeld的其他文献
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{{ truncateString('Nicholas Strausfeld', 18)}}的其他基金
Collaborative Research: Origin and Evolutionary Divergence of the Pancrustacean Brain
合作研究:泛甲壳动物大脑的起源和进化分歧
- 批准号:
1754798 - 财政年份:2018
- 资助金额:
$ 29万 - 项目类别:
Continuing Grant
2005 Neuroethology Gordon Research Conferences
2005 年神经行为学戈登研究会议
- 批准号:
0451541 - 财政年份:2005
- 资助金额:
$ 29万 - 项目类别:
Standard Grant
SGER: Using Split-Brains to Determine the Role of the Mushroom Body Lobes in Learning and Memory
SGER:利用裂脑确定蘑菇体叶在学习和记忆中的作用
- 批准号:
0411958 - 财政年份:2004
- 资助金额:
$ 29万 - 项目类别:
Standard Grant
Interactive Insect Neuroanatomy Databases for the World Wide Web
万维网交互式昆虫神经解剖学数据库
- 批准号:
9723657 - 财政年份:1997
- 资助金额:
$ 29万 - 项目类别:
Continuing Grant
"FLYBRAIN," The First in a Federation of Databases for Insect Neurobiology
“FLYBRAIN”,昆虫神经生物学数据库联盟中的第一个
- 批准号:
9507217 - 财政年份:1995
- 资助金额:
$ 29万 - 项目类别:
Continuing Grant
SGER: Neural Systems and Neurogenetic Analysis of Memory Centers
SGER:记忆中心的神经系统和神经遗传学分析
- 批准号:
9316729 - 财政年份:1993
- 资助金额:
$ 29万 - 项目类别:
Standard Grant
Synaptic Organization in a Simple Olfactory System
简单嗅觉系统中的突触组织
- 批准号:
9011012 - 财政年份:1991
- 资助金额:
$ 29万 - 项目类别:
Continuing Grant
Acquisition of a Computer-Based System for Research on Neuronal Processes
获取用于神经元过程研究的计算机系统
- 批准号:
8716063 - 财政年份:1988
- 资助金额:
$ 29万 - 项目类别:
Standard Grant
Neural Circuitry for Polarized-Light Perception
偏振光感知的神经电路
- 批准号:
8719315 - 财政年份:1988
- 资助金额:
$ 29万 - 项目类别:
Continuing Grant
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