CAREER: Development of Nanofabrication Techniques for Self-assembled Monolayer Based Biosensors
CAREER: Development of Nanofabrication Techniques for Self-assembled Monolayer Based Biosensors
批准号:
9733400
负责人:
Gang-Yu Liu
金额:
$27.5万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-02-15 至 2002-01-31
中文摘要
这个教师早期职业发展(CAREER)项目,在支持 分析和表面化学计划,侧重于使用新的 刘教授和她的学生在韦恩州立大学开发的技术 大学非常精确地修改表面, 单层。 正在开发修改方法,以允许研究 生物识别过程,并利用其特异性开发新的 在非常小的(亚微米)尺度上的化学传感器类型。 这 CAREER研究项目还涉及新表面的引入 化学课程和实验室纳入研究生和本科生 课程。 参与一项新的“智能传感器和智能 刘教授和她的学生的设备课程将提高 这种跨学科研究的可能结果。 先进的材料加工方法与 不断扩展的分子生物学领域具有广泛的意义。 刘教授和她在韦恩州立大学的学生已经开发出 微加工方法,为组装提供了很大的希望, 允许研究生物识别过程的设备, 可以进一步用于产生极其 特异性高。 这种研究的结果可以预见, 扩展到新一代的环境和生物监测器。 刘教授扩展了传感器开发的跨学科性质 计划的研究生和本科课程,介绍她 学生对化学研究的新思维方式。
英文摘要
This Faculty Early Career Development (CAREER) project, supported in the Analytical and Surface Chemistry Program, focuses on the use of new technology developed by Professor Liu and her students at Wayne State University to very precisely modify surfaces incorporating self-assembled monolayers. Modification methods are being developed to allow the study of biorecognition processes and to use their specificity to develop new types of chemical sensors on very small (sub-micrometer) scales. This CAREER research project also involves the introduction of new surface chemistry courses and laboratories into the graduate and undergraduate curricula. Participation in a novel `Smart Sensor and Intelligent Devices`course by Professor Liu and her students will enhance the possible outcomes of this sort of interdisciplinary research. The integration of advanced materials processing methods and the expanding field of molecular biology has broadranging implications. Professor Liu and her students at Wayne State University have developed microfabrication methodologies which hold great promise for the assembly of devices which allow for the study of biorecognition processes which can be further utilized for the creation of sensor devices of extremely high specificity. The outcome of such research can be envisioned to extend to a new generation of environmental and biological monitors. Professor Liu extends the interdisciplinary nature of sensor development program to the graduate and undergraduate curricula to introduce her students to new ways of thinking about chemical research.
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