Hypothesis Grounded Laboratories in Physiology and Neurobiology

生理学和神经生物学的假设实验室

基本信息

  • 批准号:
    9751261
  • 负责人:
  • 金额:
    $ 3.23万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    1997
  • 资助国家:
    美国
  • 起止时间:
    1997-06-01 至 2001-05-31
  • 项目状态:
    已结题

项目摘要

Laboratory experiences have been to enhance student participation in the scientific process at the introductory and thesis levels. Introductory courses emphasize small group discussions, self-directed experimental design, quantitative analysis, and scientific writing. This project is creatine a bridge to thesis -level research using student designed research projects in intermediate- and upper-level courses. Students are being taught to apply and develop the skills they learned in introductory classes towards hypothesis formulation and recognition of the frame of reference they use in testing a hypothesis. In collaborative laboratory projects of 3 weeks, in intermediate-level courses and in coordinated semester long research and seminar projects, students are focusing on making distinctions between "what" questions (descriptive science), "how" questions (mechanistic science that focuses on proximate causation). and "why" questions (applied or design science that focuses on ultimate causation). They are addressing hypotheses at several levels of biological organization and using multiple methods of data analysis. This approach provides the curriculum with an effective transition from introductory-level investigates to upper-level thesis project. This goal is being achieved by coordinating laboratory experiences in sophomore- junior- and senior-level courses in neurobiology, animal physiology, physiology of locomotion, and drug actions in the nervous system, as well as in research and seminar courses in animal physiology and neurobiology.
实验室的经验已经提高了学生在入门和论文水平的科学过程的参与。导论课程强调小组讨论、自主实验设计、定量分析和科学写作。这个项目是建立一个桥梁,论文水平的研究使用学生设计的研究项目在中级和高级课程。学生们被教导应用和发展他们在入门课上学到的技能,以制定假设和识别他们在测试假设时使用的参考框架。在为期三周的合作实验室项目、中级课程和协调的学期研究和研讨会项目中,学生们专注于区分“什么”问题(描述性科学)和“如何”问题(关注近似因果关系的机械科学)。以及“为什么”的问题(关注最终因果关系的应用科学或设计科学)。他们在生物组织的几个层次上处理假设,并使用多种数据分析方法。这种方法为课程提供了从入门级调查到高级论文项目的有效过渡。这一目标是通过协调二、三、四年级神经生物学、动物生理学、运动生理学和神经系统药物作用课程的实验室经验,以及动物生理学和神经生物学的研究和研讨会课程来实现的。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Nancy Kleckner其他文献

The Scaffolding Subunit of PP2A is a Coherent Linear Elastic Object That Can Transmit Mechanical Information Along Its Length
  • DOI:
    10.1016/j.bpj.2008.12.262
  • 发表时间:
    2009-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Alison E. Grinthal;Ivana Adamovic;Martin Karplus;Nancy Kleckner
  • 通讯作者:
    Nancy Kleckner
Chiasma formation: chromatin/axis interplay and the role(s) of the synaptonemal complex
  • DOI:
    10.1007/s00412-006-0055-7
  • 发表时间:
    2006-03-23
  • 期刊:
  • 影响因子:
    2.300
  • 作者:
    Nancy Kleckner
  • 通讯作者:
    Nancy Kleckner
Photonic and Magnetic Force Micro-piston: An integrated force/microfluidic device for investigating expansion and compression stress in chromatin/chromosomes and their roles in chromosome function.
  • DOI:
    10.1016/j.bpj.2008.12.175
  • 发表时间:
    2009-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Jay K. Fisher;Romain Koszul;Mara Prentiss;Nancy Kleckner
  • 通讯作者:
    Nancy Kleckner
Formation Of RecA Filament During The Mechanical Unzipping Of dsDNA To ssDNA: Competition With SSB Differentially Controls RecA Mediated SOS Response And Replication Repair
  • DOI:
    10.1016/j.bpj.2008.12.201
  • 发表时间:
    2009-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Carlo Zambonelli;Claudia Danilowicz;Nancy Kleckner;Mara Prentiss
  • 通讯作者:
    Mara Prentiss
Study Of Sequence Dependent Homolog Pairing With A Single Molecule Assay
  • DOI:
    10.1016/j.bpj.2008.12.1737
  • 发表时间:
    2009-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Claudia Danilowicz;Chiu H. Lee;Kristi Hatch;Vincent W. Coljee;Nancy Kleckner;Mara Prentiss
  • 通讯作者:
    Mara Prentiss

Nancy Kleckner的其他文献

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{{ truncateString('Nancy Kleckner', 18)}}的其他基金

RUI: Characterization of Glutamate Receptors in the Pond Snails, Helisoma Trivolvis and Biomphalaria Glabrata
RUI:池塘蜗牛、Helisoma Trivolvis 和 Bimphalaria Glabrata 中谷氨酸受体的表征
  • 批准号:
    0744305
  • 财政年份:
    2008
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Standard Grant
Workshop on Site-specific Recombination and Transposition, September 22-27, 1996, Woods Hole, MA
位点特异性重组和转座研讨会,1996 年 9 月 22-27 日,马萨诸塞州伍兹霍尔
  • 批准号:
    9600629
  • 财政年份:
    1996
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Standard Grant
U.S.-Netherlands Cooperative Research on the Comparison of Meiotic Chromosome Metabolism in Rats and Yeast
美国-荷兰合作研究大鼠和酵母减数分裂染色体代谢的比较
  • 批准号:
    9123546
  • 财政年份:
    1992
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Standard Grant
1990 Workshop on Site-specific Recombination and Transpostion: September 12-16, 1990, Woods Hole, Massachusetts.
1990 年位点特异性重组和转座研讨会:1990 年 9 月 12-16 日,马萨诸塞州伍兹霍尔。
  • 批准号:
    9004022
  • 财政年份:
    1990
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Standard Grant
Physical Studies of the Translocatable Genetic Elements in Bacteria
细菌中可易位遗传元件的物理研究
  • 批准号:
    8820303
  • 财政年份:
    1989
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Continuing Grant
U.S.-France Cooperative Research: Biochemical and Genetic Dissection of Tn10 Transposon Termini
美法合作研究:Tn10 转座子末端的生化和遗传解剖
  • 批准号:
    8715027
  • 财政年份:
    1988
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Standard Grant
Synaptonemal Complexes and Meiotic Chromosome Metabolism in Yeast
酵母中的联会复合体和减数分裂染色体代谢
  • 批准号:
    8711551
  • 财政年份:
    1987
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Continuing Grant
Physical Studies of the Translocatable Genetic Elements in Bacteria
细菌中可易位遗传元件的物理研究
  • 批准号:
    8518930
  • 财政年份:
    1986
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Continuing Grant
Genetic and Physical Studies of Translocatable Genetic Elements in Bacteria
细菌中可易位遗传元件的遗传学和物理研究
  • 批准号:
    8303415
  • 财政年份:
    1983
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Continuing Grant
Translocatable Genetic Elements in Bacteria
细菌中的可易位遗传元件
  • 批准号:
    7923508
  • 财政年份:
    1980
  • 资助金额:
    $ 3.23万
  • 项目类别:
    Continuing Grant

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