Thermodynamics and Kinetics of Protein Aggregations
Thermodynamics and Kinetics of Protein Aggregations
批准号:
9901054
负责人:
Harvey Blanch
金额:
$39.87万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-09-01 至 2003-08-31
中文摘要
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英文摘要
The objective of this project is to use a combination of experiment and theory/simulations to study protein aggregation as a competitive process to folding at high protein concentrations. One strategy will be to study, by experiment, the influence of specific interactions between amino acid residues and secondary structure on the stability of aggregates vs. the native three-dimensional structure. A secondary strategy will be to determine, from computer simulations and theory, the general characteristics of minimal models of heterogeneous polymers that can either aggregate or fold.
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会议论文
Engineering Protein Aggregation and Fibril Formation
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批准号:0432625
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项目类别:Continuing Grant
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资助金额:$49.92万
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财政年份:2005
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负责人:Harvey Blanch
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依托单位:
SGER: Tissue Engineering of Sponge Cells for Biopharmaceuticals
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批准号:0337080
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项目类别:Standard Grant
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资助金额:$5.05万
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财政年份:2003
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负责人:Harvey Blanch
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依托单位:
Thermodynamics and Kinetics of Protein Aggregation
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批准号:0118208
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项目类别:Continuing Grant
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资助金额:$56.76万
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财政年份:2001
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负责人:Harvey Blanch
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依托单位:
Molecular Thermodynamics of Protein Interactions; Applications to Protein Separations
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批准号:9530793
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项目类别:Continuing Grant
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资助金额:$73.99万
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财政年份:1996
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负责人:Harvey Blanch
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依托单位:
Bio-Molecular Thermodynamics of Protein Precipitation in Aqueous Solutions
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批准号:9214653
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项目类别:Continuing Grant
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资助金额:$18.0万
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财政年份:1993
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负责人:Harvey Blanch
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依托单位:
Enzyme Design and Catalytic Function for the Production of Novel Materials
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批准号:9119237
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项目类别:Continuing Grant
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资助金额:$68.4万
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财政年份:1992
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负责人:Harvey Blanch
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依托单位:
Molecular Thermodynamics of Protein Precipitation in AqueousSolution
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批准号:8914849
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项目类别:Continuing Grant
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资助金额:$30.5万
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财政年份:1990
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负责人:Harvey Blanch
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依托单位:
Support of the Tenth Enzyme Engineering Conference, September 24-29, l989
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批准号:8912237
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项目类别:Standard Grant
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资助金额:$1.5万
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财政年份:1989
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负责人:Harvey Blanch
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依托单位:
Enzyme Design and Catalytic Function for Production of NovelMaterials
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批准号:8807179
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项目类别:Continuing Grant
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资助金额:$76.62万
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财政年份:1988
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负责人:Harvey Blanch
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依托单位:
Engineering Research Equipment Grant: Low-Angle Laser Light-Scattering Photometer and HPLC Size Exclusion Chromatography System
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批准号:8705530
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项目类别:Standard Grant
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资助金额:$8.09万
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财政年份:1987
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负责人:Harvey Blanch
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依托单位:
Travel to Attend: Ninth Engineering Foundation Conference on Enzyme Engineering to be held in Santa Barbara, California, October 4-9, 1987
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批准号:8705074
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项目类别:Standard Grant
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资助金额:$1.6万
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财政年份:1987
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负责人:Harvey Blanch
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依托单位:
Mass Transfer and Thermodynamics for Biological Production of Chemicals
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批准号:8715908
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项目类别:Continuing Grant
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资助金额:$20.0万
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财政年份:1987
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负责人:Harvey Blanch
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依托单位:
Industry/University Cooperative Research Project: Thermo- dynamics and Transport for Reaction and Recovery of Biomolecules in Aqueous and Non-Aqueous Systems
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批准号:8513642
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项目类别:Standard Grant
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资助金额:$17.0万
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财政年份:1986
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负责人:Harvey Blanch
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依托单位:
Engineering Research Equipment Grant: High Performance Liquid Chromatography
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批准号:8505848
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项目类别:Standard Grant
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资助金额:$4.8万
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财政年份:1985
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负责人:Harvey Blanch
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依托单位:
Bubble Coalescence in Gas Liquid Contactors
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批准号:8313334
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项目类别:Continuing Grant
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资助金额:$18.58万
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财政年份:1984
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负责人:Harvey Blanch
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依托单位:
Special Foreign Currency Travel Support (In Indian Currency)To Attend the Symposium on Future Resources of Raw Materials; Bombay, India; March 22-31, 1980
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批准号:7926506
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项目类别:Standard Grant
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资助金额:$0.19万
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财政年份:1980
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负责人:Harvey Blanch
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依托单位:
Bubble Size and Fungal Morphology in Fermentation Systems
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批准号:7912024
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项目类别:Continuing Grant
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资助金额:$13.23万
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财政年份:1980
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负责人:Harvey Blanch
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依托单位:
Mechanism and Kinetics of Hydrocarbon Utilization By Microorganisms
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批准号:7910114
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项目类别:Standard Grant
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资助金额:$0.71万
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财政年份:1979
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负责人:Harvey Blanch
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依托单位:
Engineering Foundation Conference--Mass Transfer and Scale-Up of Fermentations
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批准号:7710037
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项目类别:Standard Grant
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资助金额:$1.0万
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财政年份:1977
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负责人:Harvey Blanch
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依托单位:
Non-Newtonian Fermentation Mixtures: Mass Transfer and Rheology
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批准号:7617004
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项目类别:Standard Grant
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资助金额:$11.63万
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财政年份:1976
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负责人:Harvey Blanch
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依托单位:
国内基金
海外基金
基于Hydrodynamics-Reaction Kinetics耦合模型的厌氧膨胀床反应器三相流场数值模拟及生态-水力响应机制解析
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批准号:51078108
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项目类别:面上项目
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资助金额:36.0万元
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批准年份:2010
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负责人:丁杰
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依托单位: