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Thermodynamics and Kinetics of Protein Aggregations

Thermodynamics and Kinetics of Protein Aggregations
蛋白质聚集体的热力学和动力学
批准号:
9901054
负责人:
Harvey Blanch
金额:
$39.87万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-09-01 至 2003-08-31

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中文摘要
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英文摘要
The objective of this project is to use a combination of experiment and theory/simulations to study protein aggregation as a competitive process to folding at high protein concentrations. One strategy will be to study, by experiment, the influence of specific interactions between amino acid residues and secondary structure on the stability of aggregates vs. the native three-dimensional structure. A secondary strategy will be to determine, from computer simulations and theory, the general characteristics of minimal models of heterogeneous polymers that can either aggregate or fold.
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Engineering Protein Aggregation and Fibril Formation
  • 批准号:
    0432625
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $49.92万
  • 财政年份:
    2005
  • 负责人:
    Harvey Blanch
  • 依托单位:
SGER: Tissue Engineering of Sponge Cells for Biopharmaceuticals
  • 批准号:
    0337080
  • 项目类别:
    Standard Grant
  • 资助金额:
    $5.05万
  • 财政年份:
    2003
  • 负责人:
    Harvey Blanch
  • 依托单位:
Thermodynamics and Kinetics of Protein Aggregation
  • 批准号:
    0118208
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $56.76万
  • 财政年份:
    2001
  • 负责人:
    Harvey Blanch
  • 依托单位:
Molecular Thermodynamics of Protein Interactions; Applications to Protein Separations
  • 批准号:
    9530793
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $73.99万
  • 财政年份:
    1996
  • 负责人:
    Harvey Blanch
  • 依托单位:
国内基金
海外基金
基于Hydrodynamics-Reaction Kinetics耦合模型的厌氧膨胀床反应器三相流场数值模拟及生态-水力响应机制解析
  • 批准号:
    51078108
  • 项目类别:
    面上项目
  • 资助金额:
    36.0万元
  • 批准年份:
    2010
  • 负责人:
    丁杰
  • 依托单位: