Isomerizations of Isotopically Labeled Hydrocarbons

同位素标记的烃的异构化

• 批准号: 9902184
• 负责人: John Baldwin
• 金额: $ 40.5万
• 依托单位: Syracuse University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-01 至 2003-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9902184&HistoricalAwards=false
• 关键词: Isomerizations; Isotopically; Labeled; Hydrocarbons

This project explores the mechanism of thermal reactions of relatively small hydrocarbon molecules in order to probe more deeply the characteristics of the chemical transformations which convert them into other structures. Analogs of these small molecules will be labelled with stable isotopes, which will serve as markers in the reactants. A more comprehensive view of the reactions themselves may be gained through determining the disposition of isotopic labels in the products formed. Insights as to reaction mechanisms and a stimulus to theoretical, molecular quantum mechanics-based attempts to comprehend the reactions will result.With this Award, the Organic and Macromolecular Chemistry Program continues support for the research of Professor John E. Baldwin of Syracuse University. Professor Baldwin selects examples of reactions of interest involving relatively small molecules. These molecules are synthesized while incorporating a nonradioactive isotope of carbon and/or hydrogen at specific sites, and the reaction of interest is then carried out. By tracking the fate of the isotope, information into the minute goings-on of the reaction can be gathered, building toward a fuller understanding of the fundamental nature of what scientists refer to as a "chemical reaction."

本项目探索相对较小的碳氢化合物分子的热反应机理，以更深入地探索将其转化为其他结构的化学转化的特征。这些小分子的类似物将被标记上稳定的同位素，作为反应物中的标记。通过确定形成的产物中的同位素标记的配置，可以获得对反应本身的更全面的看法。通过这个奖项，有机和高分子化学项目将继续支持锡拉丘兹大学约翰·E·鲍德温教授的研究。鲍德温教授选择了涉及相对较小分子的感兴趣的反应的例子。这些分子是在特定位置结合碳和/或氢的非放射性同位素时合成的，然后进行感兴趣的反应。通过追踪同位素的命运，可以收集反应的微小过程的信息，从而更全面地理解科学家所说的“化学反应”的根本性质。