Synthetic Organosulfur Chemistry

有机硫合成化学

• 批准号: 9906566
• 负责人: Eric Block
• 金额: $ 60万
• 依托单位: SUNY at Albany
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-15 至 2005-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9906566&HistoricalAwards=false
• 关键词: Synthetic; Organosulfur; Chemistry

This project focuses on the chemistry of organic compounds of sulfur and selenium. Broad studies of the chemical and physical properties of a variety of S- and Se-heterocycles will be carried out. Specific methodological studies include those directed toward the development of polyfunctional sulfonylethenes for use as cumulene equivalents in Diels-Alder reactions. Several interesting natural products are targeted for total synthesis to explore issues surrounding the manipulation of compounds containing multiple sulfur-based functional groups.With this Award, the Organic and Macromolecular Chemistry Program continues its support for the research of Professor Eric Block of the State University of New York at Albany. Professor Block explores the chemistry of organic molecules containing sulfur and selenium atoms. Such molecules can be used to modify the structures of other organic compounds and are also found in nature. Further study of novel forms of these molecules will uncover new and useful reactions and reagents. Several naturally occuring compounds will be synthesized in order to learn more about how to carry out reactions on molecules that may have more than one sulfur atom.

这个项目的重点是硫和硒的有机化合物的化学。将对各种S和硒杂环的化学性质和物理性质进行广泛的研究。具体的方法学研究包括那些针对开发用作Diels-Alder反应中的异丁烯等效物的多官能团磺酰乙烯的研究。几种有趣的天然产物被作为全合成的目标，以探索围绕包含多个硫基官能团的化合物的操纵问题。有了这个奖，有机和高分子化学计划继续支持纽约州立大学奥尔巴尼分校的Eric Block教授的研究。布洛克教授研究的是含有硫和硒原子的有机分子的化学。这种分子可以用来修饰其他有机化合物的结构，也存在于自然界中。进一步研究这些分子的新形式将发现新的有用的反应和试剂。为了更多地了解如何在可能含有一个以上硫原子的分子上进行反应，将合成几种自然产生的化合物。