Integration of GC/MS Into the Undergraudate Curriculum

将 GC/MS 纳入本科课程

• 批准号: 9952748
• 负责人: Jennifer Muzyka
• 金额: $ 3.75万
• 依托单位: Centre College of Kentucky
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-15 至 2003-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9952748&HistoricalAwards=false
• 关键词: Integration; GC; MS; Into; Undergraudate

Chemistry (12) This project uses gas chromatography/mass spectroscopy (GC/MS) experiences to enhance the undergraduate curriculum. The instrumentation is incorporated into the laboratory component of seven courses including general chemistry, organic chemistry, instrumental analysis, three advanced courses (organic, inorganic and analytical), and undergraduate research. This instrumentation adds a new and necessary dimension to the array of equipment used by students to solve real and complex problems. Based on a belief that it is important for students to comprehend the fundamental physical and chemical principles involved in GC/MS, to understand the major design features of the instrumentation, to recognize appropriate applications of the technique, and to appreciate the limitation of the data provided by GC/MS, this project will add an important practical component to courses where before it was only possible to present theoretical descriptions of GC/MS through classroom instruction. A series of experiments, beginning with the first term of general chemistry and extending through the senior year, are being adapted from the educational chemical literature (primarily the Journal of Chemical Education) and implemented. Through these laboratory experiences students are learning to interpret isotopic mass and abundance data, to interpret fragmentation patterns, to analyze complex mixtures and to make qualitative identifications through use of library match software. They are also developing a sound background in the fundamental operating principles of the technique. The unique feature of this project is the sequenced manner in which GC/MS experiences are built into the curriculum at three levels and integrated to develop the student's comprehension of the technique through multiple direct experiences.

化学（12）这个项目使用气相色谱/质谱（GC/MS）的经验，以提高本科课程。 仪器被纳入七门课程的实验室组成部分，包括普通化学，有机化学，仪器分析，三门高级课程（有机，无机和分析）和本科研究。 这种仪器为学生解决真实的和复杂的问题所使用的设备阵列增加了一个新的和必要的维度。 基于这样一种信念，即学生理解GC/MS中涉及的基本物理和化学原理、理解仪器的主要设计特征、认识该技术的适当应用以及理解GC/MS提供的数据的局限性是重要的，这个项目将为课程增加一个重要的实践部分，以前只能通过课堂教学来介绍GC/MS的理论描述。 一系列的实验，从普通化学的第一个学期开始，一直延伸到高年级，正在从教育化学文献（主要是化学教育杂志）改编并实施。通过这些实验室的经验，学生正在学习解释同位素质量和丰度数据，解释碎裂模式，分析复杂的混合物，并通过使用库匹配软件进行定性鉴定。他们还在该技术的基本操作原理方面建立了良好的背景。 该项目的独特之处在于，GC/MS经验以有序的方式在三个层次上融入课程，并通过多种直接经验整合以培养学生对该技术的理解。