"Integration of GC-MS into the Undergraduate Chemistry Curriculum"

“GC-MS 融入本科化学课程”

• 批准号: 9750833
• 负责人: Perry Reeves
• 金额: $ 3.15万
• 依托单位: Abilene Christian University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-15 至 2000-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9750833&HistoricalAwards=false
• 关键词: Integration; GC; MS; into; Undergraduate

This project is based on the need for a gas chromatograph/mass spectrometer (GC/MS) system for use in the improvement of the undergraduate chemistry curriculum. Theoretical discussions of mass spectrometry, as well as actual use of the instrument, can be incorporated into most of the lower level courses. The basic principles of mass spectrometry and its use in determining isotopic distributions of various elements can be introduced in the freshman-level General Chemistry course. Also in this course (taken by all pre-health-professions majors), the use of GC/MS in biomedical screening and in the detection of hazardous materials in water can be discussed and experiments conducted. In the Organic Chemistry course, GC/MS can be used to determine the composition of various natural products and to determine the identity of various halogenated hydrocarbons, as well as structural isomers of esters. The junior/senior-level Analytical Chemistry courses focus on theoretical aspects of the instrumentation and detailed analyses of fragmentation patterns. In Physical Chemistry, diffusion rates of liquids and gases are measured. The department is also in the process of developing a bachelor's degree program with an Environmental Chemistry emphasis. One of the components of this program is a course in which analyses of water and soil samples are conducted according to EPA guidelines. Thus, this project affects a wide range of students (including both chemistry and non-chemistry-majors), whose career fields make use of GC/MS technology. *

该项目是基于需要一个气相色谱仪/质谱仪（GC/MS）系统用于改进本科化学课程。 质谱的理论讨论，以及仪器的实际使用，可以纳入大多数较低水平的课程。 质谱法的基本原理及其在确定各种元素的同位素分布中的应用可以在新生水平的普通化学课程中介绍。 此外，在这门课程（采取的所有预健康专业的专业），使用GC/MS在生物医学筛选和水中有害物质的检测可以讨论和实验进行。 在有机化学课程中，GC/MS可用于确定各种天然产物的组成，并确定各种卤代烃的身份，以及酯的结构异构体。 初级/高级分析化学课程侧重于仪器的理论方面和碎片模式的详细分析。 在物理化学中，测量液体和气体的扩散速率。 该部门还在开发一个以环境化学为重点的学士学位课程。 该计划的组成部分之一是根据EPA指南进行水和土壤样品分析的课程。 因此，该项目影响了广泛的学生（包括化学和非化学专业），他们的职业领域利用GC/MS技术。 *